A panel of experts convened by the US Food and Drug Administration recommended the Covid-19 vaccines by Moderna and Pfizer-BioNTech on Wednesday for the nation's youngest children.
Formal authorisations should follow quickly, with the first shots expected by next week after expected approvals by the Centres for Disease Control and Prevention.
“This recommendation does fill a significant unmet need for a really ignored younger population,” said Michael Nelson, a professor of medicine at the University of Virginia.
Prof Nelson was one of the 21 experts who unanimously said the benefits of the Moderna vaccine outweighed the risks.
Opening the meeting, senior FDA scientist Dr Peter Marks said that despite studies showing most children had now been infected with coronavirus, the high rate of hospital admissions among infants, toddlers and young children during last winter's Omicron wave showed the urgent need for vaccination.
“We are dealing with an issue where we have to be careful we don't become numb to the paediatric deaths because of the overwhelming number of older deaths,” Dr Marks said.
The US has recorded 480 Covid-19 deaths in the 0-4 age group so far in the pandemic, official data shows, far higher than even a “terrible flu season”, he said.
As of May, there had been 45,000 hospital admissions in that age group, nearly a quarter of whom required intensive care.
Both vaccines were tested in trials of thousands of children. They were found to bring on similar levels of mild side effects as in older age groups and caused similar levels of antibodies.
Efficacy against infection was higher for Pfizer, with the company placing it at 80 per cent, compared to Moderna's estimates of 51 per cent for children aged six months to 2 years and 37 per cent for those aged between 2 and 5.
But the Pfizer figure is based on very few cases and is thus considered preliminary.
It also takes three doses to achieve its protection, with the third shot given eight weeks after the second, and 11 weeks after the first.
Moderna's vaccine should provide strong protection against severe disease after two doses, given four weeks apart, and the company is studying a booster that would raise efficacy levels against mild disease.
But Moderna's decision to go with a higher dose is associated with higher levels of fever in reaction to the vaccine compared to Pfizer.
White House officials last week said the distribution of 10 million shots to pharmacies and doctors' offices could begin as soon as June 21.
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The Voice of Hind Rajab
Starring: Saja Kilani, Clara Khoury, Motaz Malhees
Director: Kaouther Ben Hania
Rating: 4/5
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Funding: $40 million
Investor: Opportunity Venture (Asia)
UAE currency: the story behind the money in your pockets
Scoreline
Real Madrid 1
Ronaldo (53')
Atletico Madrid 1
Griezmann (57')
Red Sparrow
Dir: Francis Lawrence
Starring: Jennifer Lawrence, Joel Egerton, Charlotte Rampling, Jeremy Irons
Three stars
If you go...
Etihad Airways flies from Abu Dhabi to Kuala Lumpur, from about Dh3,600. Air Asia currently flies from Kuala Lumpur to Terengganu, with Berjaya Hotels & Resorts planning to launch direct chartered flights to Redang Island in the near future. Rooms at The Taaras Beach and Spa Resort start from 680RM (Dh597).
MATCH INFO
Uefa Champions League, semi-final result:
Liverpool 4-0 Barcelona
Liverpool win 4-3 on aggregate
Champions Legaue final: June 1, Madrid
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Second ODI
England 322-7 (50 ovs)
India 236 (50 ovs)
England win by 86 runs
Next match: Tuesday, July 17, Headingley
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England XI for second Test
Rory Burns, Keaton Jennings, Ben Stokes, Joe Root (c), Jos Buttler, Moeen Ali, Ben Foakes (wk), Sam Curran, Adil Rashid, Jack Leach, James Anderson
LA LIGA FIXTURES
Saturday (UAE kick-off times)
Leganes v Getafe (12am)
Levante v Alaves (4pm)
Real Madrid v Sevilla (7pm)
Osasuna v Valladolid (9.30pm)
Sunday
Eibar v Atletico Madrid (12am)
Mallorca v Valencia (3pm)
Real Betis v Real Sociedad (5pm)
Villarreal v Espanyol (7pm)
Athletic Bilbao v Celta Vigo (9.30pm)
Monday
Barcelona v Granada (12am)
BUNDESLIGA FIXTURES
Saturday, May 16 (kick-offs UAE time)
Borussia Dortmund v Schalke (4.30pm)
RB Leipzig v Freiburg (4.30pm)
Hoffenheim v Hertha Berlin (4.30pm)
Fortuna Dusseldorf v Paderborn (4.30pm)
Augsburg v Wolfsburg (4.30pm)
Eintracht Frankfurt v Borussia Monchengladbach (7.30pm)
Sunday, May 17
Cologne v Mainz (4.30pm),
Union Berlin v Bayern Munich (7pm)
Monday, May 18
Werder Bremen v Bayer Leverkusen (9.30pm)