A patient taken by ambulance to Royal London Hospital in East London. Getty Images
A patient taken by ambulance to Royal London Hospital in East London. Getty Images
A patient taken by ambulance to Royal London Hospital in East London. Getty Images
A patient taken by ambulance to Royal London Hospital in East London. Getty Images

Covid 'could have been five times as bad if Omicron was first strain'


Gillian Duncan
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If Omicron had been the first Covid strain to emerge in Wuhan in 2020, there could have been significantly more deaths worldwide, an eminent immunologist has said.

Sir John Bell, regius professor of medicine at the University of Oxford, said the impact of the pandemic “could have been a lot worse” with the highly infectious variant.

He was speaking after comments by former Chinese government scientist Prof George Gao, who said the possibility the coronavirus leaked from a laboratory should not be ruled out.

Speaking on BBC Radio 4’s Today programme, Sir John said he did not think the evidence of whether it emerged from a lab, or naturally, was conclusive either way.

“I would put it to you that it actually doesn’t make any difference,” he said. “We know historically that we do get pathogens that come from the animal kingdom that get into man that cause these sorts of outbreaks.

“And we also know that labs that look after these very pathogenic viruses do leak.”

How the world responds to be ready for another pandemic is most important, he said.

Sir John said he had recently held a meeting attended by Prof Gao, at which Covid modelling by a company called Airfinity was discussed.

“They did the modelling around the idea that if the first virus that appeared in Wuhan had not been the Wuhan strain, but had been the Omicron strain, which we all know is much, much more infectious,” he said. “And that had hit an immunologically naive population, in other words a population that had never seen the virus before.

“The peak mortality in the UK would have been about five times what it was with the originally Wuhan strain. Remember those were pretty dark times during April and May of 2020 and I don’t think we would have wanted five times the number of people dying.

“And had it been Avian flu it would have been 15 times [higher]. So I think when we hear that there is a great pandemic coming, if either one of those things were to happen, it would be a great deal worse than what we saw.”

In an interview with the BBC, Prof Gao told Radio 4 podcast Fever: The Hunt for Covid's Origin: “You can always suspect anything. That's science. Don't rule out anything.”

Prof Gao is now vice president of the National Natural Science Foundation of China after retiring last year from the CDC, where he played a key role in the pandemic response and efforts to trace how it started.

The theory that Covid leaked accidentally from a Chinese lab resurfaced in February when the FBI's director Christopher Wray said this was where the virus had “most likely” originated, although there is no consensus among US intelligence agencies on the matter.

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Labour dispute

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- Abdullah Ishnaneh, Partner, BSA Law 

The struggle is on for active managers

David Einhorn closed out 2018 with his biggest annual loss ever for the 22-year-old Greenlight Capital.

The firm’s main hedge fund fell 9 per cent in December, extending this year’s decline to 34 percent, according to an investor update viewed by Bloomberg.

Greenlight posted some of the industry’s best returns in its early years, but has stumbled since losing more than 20 per cent in 2015.

Other value-investing managers have also struggled, as a decade of historically low interest rates and the rise of passive investing and quant trading pushed growth stocks past their inexpensive brethren. Three Bays Capital and SPO Partners & Co., which sought to make wagers on undervalued stocks, closed in 2018. Mr Einhorn has repeatedly expressed his frustration with the poor performance this year, while remaining steadfast in his commitment to value investing.

Greenlight, which posted gains only in May and October, underperformed both the broader market and its peers in 2018. The S&P 500 Index dropped 4.4 per cent, including dividends, while the HFRX Global Hedge Fund Index, an early indicator of industry performance, fell 7 per cent through December. 28.

At the start of the year, Greenlight managed $6.3 billion in assets, according to a regulatory filing. By May, the firm was down to $5.5bn. 

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• Scientists estimate there could be as many as 3 million fungal species globally
• Only about 160,000 have been officially described leaving around 90% undiscovered
• Fungi account for roughly 90% of Earth's unknown biodiversity
• Forest fungi help tackle climate change, absorbing up to 36% of global fossil fuel emissions annually and storing around 5 billion tonnes of carbon in the planet's topsoil

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Chelsea 4 (Mount 18',Werner 44', Hudson-Odoi 49', Havertz 85')

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Updated: May 30, 2023, 11:41 AM`