The US faces a steep uphill struggle in monitoring Covid-19 variants, dangerous mutations that might spread quickly, evade vaccines or kill more infected people.
Other countries, such as the UK, have established robust, nationwide surveillance programmes to identify new Covid genomes and track the spread of existing ones.
But the US has not. It ranks 32nd in the world in number of sequences completed for every 1,000 Covid cases, says Gisaid, a global database where researchers share new genomes.
While the Biden administration is promising to boost the country's sequencing efforts, it will not be easy.
The US system now in place includes a scattered collection of academic, commercial and public health laboratories that are typically underfunded and under-resourced.
This amounts to a gaping hole in national security at a time when at least three dangerous global variants have already been identified and others may yet be discovered.
“The problem is that this was never a public health lab priority,” said Michael Osterholm, director of the Centre for Infectious Disease Research and Policy at the University of Minnesota and an adviser to US President Joe Biden.
"Most of the sequencing was going on in private labs.”
Mr Osterholm said it must be made a priority.
Over the past week, federal health officials promised to increase the US ability to track variants.
“We are now scaling up both our surveillance of these and our study of these,” Rochelle Walensky, the new director of the US Centres for Disease Control and Prevention, told Fox News on Sunday.
But the administration has yet to outline concrete steps to turn the current effort into a cohesive and efficient national programme.
In the US, about 200,000 Americans test positive for Covid-19 weekly, but only about 3,000 of those tests are sequenced to hunt for mutations, according to the centre.
The US is behind nations known for their genomic processing expertise, such as the UK and Iceland, and behind Gambia, Senegal and Latvia, the Gisaid listings show.
Creating a viral surveillance network “is a public health need, but also a defence need", said Francis deSouza, chief executive of the sequencing company Illumina, which has been working with partners to help monitor the evolution of the virus.
“Understanding how the virus is mutating will tell you whether the tools you’re using to combat the virus will continue to be effective,” Mr deSouza said.
The three variants that have raised concerns among scientists and public health experts were identified in the UK, South Africa and, most recently, Brazil.
The Brazil variant was found in a Minnesota resident who had travelled to that country, the state's Department of Health said.
This suggests the variant may not yet be widely circulating in the US.
The highly transmissible UK variant has already been found in more than 20 US states.
We see case rates go up and we don't know if that's because people aren't doing the right things in terms of staying home and masking and social distancing, or whether it's a variant. We're in the dark.
The California Department of Public Health said this month that scientists had identified a variant of the coronavirus, known as L452R, in many parts of the state.
Officials said they were not yet sure whether the variant was more transmissible, but noted that it had been found among patients in large outbreaks in Santa Clara County, which health officer Dr Sara Cody called a “red flag.”
Moderna on Monday expressed concern that the South Africa variant may cause vaccination immunity to decrease more quickly.
The company said it was planning human studies for a vaccine booster to address this concern.
"When you have something that maybe is twice as readily transmitted as something else, that alone is going to cause a problem because the more people that get infected, the more people are going to get hospitalised," said Anthony Fauci, the top US infectious disease doctor, referring to the UK variant.
Sars-CoV-2, the coronavirus that causes Covid-19, mutates frequently, although not as often as the virus that causes influenza, scientists have said.
While most mutations will have no significant effect on Covid-19's ability to infect, the UK and South Africa variants appear to have the ability to infiltrate the bodies' cells better than the original form of the virus, which could make them more contagious.
The B117 variant that was detected in south-eastern England in September contributed to a surge in cases that in January sent the UK back into lockdown.
By early January, cases caused by this variant had also been identified in about 50 countries and territories, including the US, Australia, Canada, Germany, Italy, Japan, Lebanon, the Netherlands, Singapore and South Korea.
The effort to advance US sequencing began in May, when the Centres for Disease Control established a consortium of sequencing labs known as the Sars-CoV-2 Sequencing for Public Health Emergency Response, Epidemiology and Surveillance, or Spheres.
But US sequencing efforts have been spotty at best. The UK sequences about 10 per cent of its positive Covid-19 cases, while the US sequences about 0.3 per cent, Mr deSouza said.
As of January, California, with three million Covid-19 cases, sequenced more than 9,000 cases.
Texas, with more than a million cases, sequenced about 15,000.
But Virginia, where cases are approaching half a million and rising, has sequenced only seven viral genomes.
“We see case rates go up and we don’t know if that’s because people aren’t doing the right things in terms of staying home and masking and social distancing, or whether it’s a variant,” said Eric Topol, director of Scripps Research Translational Institute.
“We’re in the dark.”
2024%20Dubai%20Marathon%20Results
%3Cp%3E%3Cstrong%3EWomen%E2%80%99s%20race%3A%3C%2Fstrong%3E%0D%3Cbr%3E1.%20Tigist%20Ketema%20(ETH)%202hrs%2016min%207sec%0D%3Cbr%3E2.%20Ruti%20Aga%20(ETH)%202%3A18%3A09%0D%3Cbr%3E3.%20Dera%20Dida%20(ETH)%202%3A19%3A29%0D%3Cbr%3EMen's%20race%3A%0D%3Cbr%3E1.%20Addisu%20Gobena%20(ETH)%202%3A05%3A01%0D%3Cbr%3E2.%20Lemi%20Dumicha%20(ETH)%202%3A05%3A20%0D%3Cbr%3E3.%20DejeneMegersa%20(ETH)%202%3A05%3A42%3C%2Fp%3E%0A
UAE currency: the story behind the money in your pockets
Tailors and retailers miss out on back-to-school rush
Tailors and retailers across the city said it was an ominous start to what is usually a busy season for sales.
With many parents opting to continue home learning for their children, the usual rush to buy school uniforms was muted this year.
“So far we have taken about 70 to 80 orders for items like shirts and trousers,” said Vikram Attrai, manager at Stallion Bespoke Tailors in Dubai.
“Last year in the same period we had about 200 orders and lots of demand.
“We custom fit uniform pieces and use materials such as cotton, wool and cashmere.
“Depending on size, a white shirt with logo is priced at about Dh100 to Dh150 and shorts, trousers, skirts and dresses cost between Dh150 to Dh250 a piece.”
A spokesman for Threads, a uniform shop based in Times Square Centre Dubai, said customer footfall had slowed down dramatically over the past few months.
“Now parents have the option to keep children doing online learning they don’t need uniforms so it has quietened down.”
Scream%20VI
%3Cp%3E%3Cstrong%3EDirectors%3A%3C%2Fstrong%3E%20Matt%20Bettinelli-Olpin%20and%20Tyler%20Gillett%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EStars%3A%3C%2Fstrong%3E%20Melissa%20Barrera%2C%20Jasmin%20Savoy%20Brown%2C%20Jack%20Champion%2C%20Dermot%20Mulroney%2C%20Jenna%20Ortega%2C%20Hayden%20Panettiere%20and%20Courteney%20Cox%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3ERating%3A%3C%2Fstrong%3E%203%2F5%3C%2Fp%3E%0A
SCORES
Multiply Titans 81-2 in 12.1 overs
(Tony de Zorzi, 34)
bt Auckland Aces 80 all out in 16 overs
(Shawn von Borg 4-15, Alfred Mothoa 2-11, Tshepo Moreki 2-16).
THE BIG THREE
NOVAK DJOKOVIC
19 grand slam singles titles
Wimbledon: 5 (2011, 14, 15, 18, 19)
French Open: 2 (2016, 21)
US Open: 3 (2011, 15, 18)
Australian Open: 9 (2008, 11, 12, 13, 15, 16, 19, 20, 21)
Prize money: $150m
ROGER FEDERER
20 grand slam singles titles
Wimbledon: 8 (2003, 04, 05, 06, 07, 09, 12, 17)
French Open: 1 (2009)
US Open: 5 (2004, 05, 06, 07, 08)
Australian Open: 6 (2004, 06, 07, 10, 17, 18)
Prize money: $130m
RAFAEL NADAL
20 grand slam singles titles
Wimbledon: 2 (2008, 10)
French Open: 13 (2005, 06, 07, 08, 10, 11, 12, 13, 14, 17, 18, 19, 20)
US Open: 4 (2010, 13, 17, 19)
Australian Open: 1 (2009)
Prize money: $125m
CRICKET%20WORLD%20CUP%20LEAGUE%202
%3Cp%3EMannofield%2C%20Aberdeen%3Cbr%3E%3Cbr%3EAll%20matches%20start%20at%202pm%20UAE%20time%20and%20will%20be%20broadcast%20on%20icc.tv%3Cbr%3E%3Cbr%3E%3Cstrong%3EUAE%20fixtures%3C%2Fstrong%3E%3Cbr%3E%3Cbr%3EWednesday%2C%20Aug%2010%20%E2%80%93%20Scotland%20v%20UAE%3Cbr%3EThursday%2C%20Aug%2011%20-%20UAE%20v%20United%20States%3Cbr%3ESaturday%2C%20Aug%2014%20%E2%80%93%20Scotland%20v%20UAE%3Cbr%3EMonday%2C%20Aug%2015%20%E2%80%93%20UAE%20v%20United%20States%3Cbr%3E%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EUAE%20squad%3C%2Fstrong%3E%3Cbr%3E%3Cbr%3EAhmed%20Raza%20(captain)%2C%20Chirag%20Suri%2C%20Muhammad%20Waseem%2C%20Vriitya%20Aravind%2C%20CP%20Rizwan%2C%20Basil%20Hameed%2C%20Rohan%20Mustafa%2C%20Zawar%20Farid%2C%20Kashif%20Daud%2C%20Karthik%20Meiyappan%2C%20Zahoor%20Khan%2C%20Junaid%20Siddique%2C%20Sabir%20Ali%2C%20Alishan%20Sharafu%3Cbr%3E%3Cbr%3E%3Cstrong%3ETable%3C%2Fstrong%3E%20(top%20three%20teams%20advance%20directly%20to%20the%202023%20World%20Cup%20Qualifier)%3Cbr%3E%3Cbr%3E1.%20Oman%2036%2021%2013%201%201%2044%3Cbr%3E2.%20Scotland%2024%2016%206%200%202%2034%3Cbr%3E3.%20UAE%2022%2012%208%201%201%2026%3Cbr%3E--%3Cbr%3E4.%20Namibia%2018%209%209%200%200%2018%3Cbr%3E5.%20United%20States%2024%2011%2012%201%200%2023%3Cbr%3E6.%20Nepal%2020%208%2011%201%200%2017%3Cbr%3E7.%20Papua%20New%20Guinea%2020%201%2019%200%200%202%3C%2Fp%3E%0A
The candidates
Dr Ayham Ammora, scientist and business executive
Ali Azeem, business leader
Tony Booth, professor of education
Lord Browne, former BP chief executive
Dr Mohamed El-Erian, economist
Professor Wyn Evans, astrophysicist
Dr Mark Mann, scientist
Gina MIller, anti-Brexit campaigner
Lord Smith, former Cabinet minister
Sandi Toksvig, broadcaster
if you go
The flights
Etihad and Emirates fly direct to Kolkata from Dh1,504 and Dh1,450 return including taxes, respectively. The flight takes four hours 30 minutes outbound and 5 hours 30 minute returning.
The trains
Numerous trains link Kolkata and Murshidabad but the daily early morning Hazarduari Express (3’ 52”) is the fastest and most convenient; this service also stops in Plassey. The return train departs Murshidabad late afternoon. Though just about feasible as a day trip, staying overnight is recommended.
The hotels
Mursidabad’s hotels are less than modest but Berhampore, 11km south, offers more accommodation and facilities (and the Hazarduari Express also pauses here). Try Hotel The Fame, with an array of rooms from doubles at Rs1,596/Dh90 to a ‘grand presidential suite’ at Rs7,854/Dh443.
How%20champions%20are%20made
%3Cp%3E%0D%3Cstrong%3EDiet%3C%2Fstrong%3E%20%0D%3Cbr%3E7am%20-%20Protein%20shake%20with%20oats%20and%20fruits%0D%3Cbr%3E10am%20-%205-6%20egg%20whites%0D%3Cbr%3E1pm%20-%20White%20rice%20or%20chapati%20(Indian%20bread)%20with%20chicken%0D%3Cbr%3E4pm%20-%20Dry%20fruits%20%0D%3Cbr%3E7.30pm%20-%20Pre%20workout%20meal%20%E2%80%93%20grilled%20fish%20or%20chicken%20with%20veggies%20and%20fruits%0D%3Cbr%3E8.30pm%20to%20midnight%20workout%0D%3Cbr%3E12.30am%20%E2%80%93%20Protein%20shake%20%0D%3Cbr%3E%3Cstrong%3ETotal%20intake%3A%3C%2Fstrong%3E%204000-4500%20calories%20%0D%3Cbr%3E%3Cstrong%3ESaidu%E2%80%99s%20weight%3A%3C%2Fstrong%3E%20110%20kg%0D%3Cbr%3E%3Cstrong%3EStats%3A%3C%2Fstrong%3E%20Biceps%2019%20inches.%20Forearms%2018%20inches%3C%2Fp%3E%0A
Brief scoreline:
Manchester United 0
Manchester City 2
Bernardo Silva 54', Sane 66'
Fines for littering
In Dubai:
Dh200 for littering or spitting in the Dubai Metro
Dh500 for throwing cigarette butts or chewing gum on the floor, or littering from a vehicle.
Dh1,000 for littering on a beach, spitting in public places, throwing a cigarette butt from a vehicle
In Sharjah and other emirates
Dh500 for littering - including cigarette butts and chewing gum - in public places and beaches in Sharjah
Dh2,000 for littering in Sharjah deserts
Dh500 for littering from a vehicle in Ras Al Khaimah
Dh1,000 for littering from a car in Abu Dhabi
Dh1,000 to Dh100,000 for dumping waste in residential or public areas in Al Ain
Dh10,000 for littering at Ajman's beaches
The%20specs
%3Cp%3E%3Cstrong%3EEngine%3A%20%3C%2Fstrong%3E2.0-litre%204-cyl%20turbo%3Cbr%3E%3Cstrong%3EPower%3A%20%3C%2Fstrong%3E190hp%20at%205%2C600rpm%3Cbr%3E%3Cstrong%3ETorque%3A%20%3C%2Fstrong%3E320Nm%20at%201%2C500-4%2C000rpm%3Cbr%3E%3Cstrong%3ETransmission%3A%20%3C%2Fstrong%3E7-speed%20dual-clutch%20auto%3Cbr%3E%3Cstrong%3EFuel%20consumption%3A%20%3C%2Fstrong%3E10.9L%2F100km%3Cbr%3E%3Cstrong%3EPrice%3A%20%3C%2Fstrong%3EFrom%20Dh119%2C900%3Cbr%3E%3Cstrong%3EOn%20sale%3A%20%3C%2Fstrong%3ENow%3C%2Fp%3E%0A
RESULTS
5pm: Wathba Stallions Cup Maiden (PA) Dh 70,000 (Dirt) 1,600m
Winner: Samau Xmnsor, Abdul Aziz Al Balushi (jockey), Ibrahim Al Hadhrami (trainer)
5.30pm: Maiden (PA) Dh 70,000 (D) 1,600m
Winner: Ottoman, Szczepan Mazur, Abdallah Al Hammadi
6pm: Maiden (PA) Dh 70,000 (D) 1,800m
Winner: Sharkh, Patrick Cosgrave, Helal Al Alawi
6.30pm: Handicap (PA) Dh 85,000 (D) 1,800m
Winner: Yaraa, Fernando Jara, Majed Al Jahouri
7pm: Handicap (PA) Dh 70,000 (D) 2,000m
Winner: Maaly Al Reef, Bernardo Pinheiro, Abdallah Al Hammadi
7.30pm: Maiden (PA) Dh 70,000 (D) 1,000m
Winner: Jinjal, Fabrice Veron, Ahmed Al Shemaili
8pm: Handicap (PA) Dh 70,000 (D) 1,000m
Winner: Al Sail, Tadhg O’Shea, Ernst Oertel