The WHO assists countries in collecting dangerous specimens and ensures labs follow appropriate biosafety and biosecurity measures. Reuters
The WHO assists countries in collecting dangerous specimens and ensures labs follow appropriate biosafety and biosecurity measures. Reuters
The WHO assists countries in collecting dangerous specimens and ensures labs follow appropriate biosafety and biosecurity measures. Reuters
The WHO assists countries in collecting dangerous specimens and ensures labs follow appropriate biosafety and biosecurity measures. Reuters

Boom in high-security bio labs brings greater pandemic risk


Thomas Harding
  • English
  • Arabic

BIOSAFETY LABS SECURITY LEVELS

Biosafety Level 1

The lowest safety level. These labs work with viruses that are minimal risk to humans.

Hand washing is required on entry and exit and potentially infectious material decontaminated with bleach before thrown away.

Must have a lock. Access limited. Lab does not need to be isolated from other buildings.

Used as teaching spaces.

Study microorganisms such as Staphylococcus which causes food poisoning.

Biosafety Level 2

These labs deal with pathogens that can be harmful to people and the environment such as Hepatitis, HIV and salmonella.

Working in Level 2 requires special training in handling pathogenic agents.

Extra safety and security precautions are taken in addition to those at Level 1

Biosafety Level 3

These labs contain material that can be lethal if inhaled. This includes SARS coronavirus, MERS, and yellow fever.

Significant extra precautions are taken with staff given specific immunisations when dealing with certain diseases.

Infectious material is examined in a biological safety cabinet.

Personnel must wear protective gowns that must be discarded or decontaminated after use.

Strict safety and handling procedures are in place. There must be double entrances to the building and they must contain self-closing doors to reduce risk of pathogen aerosols escaping.

Windows must be sealed. Air from must be filtered before it can be recirculated.

Biosafety Level 4

The highest level for biosafety precautions. Scientist work with highly dangerous diseases that have no vaccine or cure.

All material must be decontaminated.

Personnel must wear a positive pressure suit for protection. On leaving the lab this must pass through decontamination shower before they have a personal shower.

Entry is severely restricted to trained and authorised personnel. All entries are recorded.

Entrance must be via airlocks.

The risk of a devastating viral outbreak has increased significantly with the rapid increase in laboratories that handle the world's deadliest diseases, a top biosecurity expert has warned.

The World Health Organisation (WHO) faces calls to reinforce its rules and send more inspectors to Biosafety Level 4 security labs, more than 100 of which are expected worldwide within a few years.

Without greater legislation and security there was a high chance of a ‘Covid 25’ or similar virus outbreak that would harm the world’s population, said biosecurity expert Hamish de Bretton-Gordon. “The WHO say they stipulate this but it doesn’t seem anybody is policing it," he said "We need a complete review of biological security. We have to sort it out now otherwise we are going to be brought to our knees by Covid-25.”

The WHO assists countries in collecting dangerous specimens and ensures labs follow appropriate biosafety and biosecurity measures. This means that countries must meet commitments under the International Health Regulations.

The number of Level 4 labs has risen from only a handful a few decades ago to around 70 and will total more than 100 in a few years. Countries such as Iran, Syria, Sudan and North Korea are all understood to have or have been developing the labs along with India and the Philippines.

"There has been an 'eruption in growth' of Level 4 labs," Mr De Bretton-Gordon told The National. "Recent developments in the pharmaceutical industry have seen them appear all over the world dealing with the deadliest pathogens. That's a real concern."

The high-security Level 4 labs contain viruses that can be easily transmitted, causing fatal disease in humans for which there is no available vaccine or cure. Among other deadly pathogens, they will hold stores of Ebola, plague, anthrax bacteria and Marburg virus for research purposes. Many are built in earthquake and bombproof bunkers and are protected by the highest level of security.

Early Level 4 labs were started by militaries researching biological warfare but this was outlawed by the Biological Weapons Convention in 1972. Under the UN charter, proliferation of biological weapons “constitutes a threat to international peace and security”. States are obliged to prevent the manufacture or development of biological weapons.

But without tougher laws and regulations there are concerns that countries, terrorists or criminals could deliberately or accidentally release a deadly virus on the world population.

Outside established labs in Europe and the United States there are worries about security elsewhere, especially over unsubstantiated reports that Covid-19 might have escaped from the Level 4 lab in Wuhan, China.

Mr De Bretton-Gordon, who helped tackle ISIS’s biological and chemical programmes, has called for detailed legislation to govern development of labs.

“When it comes to protocols and legislation, biological is a very poor relation to the chemical world where you have the Chemical Weapons Convention, which is policed by the OPCW [Organisation for Prohibition of Chemical Weapons] and has been very successful.”

The former British Army officer, who led Nato's rapid reaction Chemical Biological Radiological and Nuclear Battalion, suggested the best way to pass laws was through the Biological Weapons Convention using weapons inspectors similar to the OPCW who have the remit to go to all countries.

The expert has already briefed the US Senate and British authorities about the proposal. He added: “The 1972 Convention is really very poor relation to chemical one. It’s poorly funded and doesn’t have anyone policing it because people thought bio was a thing of past.”

While research has been done on pandemics from SARS and MERS to Ebola it was thought scientists could handle a coronavirus outbreak.

“The thing about Covid is that it’s not very toxic and it was thought this would not create much trouble but we now know it’s brought the world to its knees and will take years to resolve it. Essentially we have been undone by a not very toxic pathogen.”

Squid Game season two

Director: Hwang Dong-hyuk 

Stars:  Lee Jung-jae, Wi Ha-joon and Lee Byung-hun

Rating: 4.5/5

The burning issue

The internal combustion engine is facing a watershed moment – major manufacturer Volvo is to stop producing petroleum-powered vehicles by 2021 and countries in Europe, including the UK, have vowed to ban their sale before 2040. The National takes a look at the story of one of the most successful technologies of the last 100 years and how it has impacted life in the UAE. 

Read part four: an affection for classic cars lives on

Read part three: the age of the electric vehicle begins

Read part two: how climate change drove the race for an alternative 

UAE currency: the story behind the money in your pockets
Sanju

Produced: Vidhu Vinod Chopra, Rajkumar Hirani

Director: Rajkumar Hirani

Cast: Ranbir Kapoor, Vicky Kaushal, Paresh Rawal, Anushka Sharma, Manish’s Koirala, Dia Mirza, Sonam Kapoor, Jim Sarbh, Boman Irani

Rating: 3.5 stars

Super heroes

Iron Man
Reduced risk of dementia
Alcohol consumption could be an issue

Hulk
Cardiac disease, stroke and dementia from high heart rate

Spider-Man
Agility reduces risk of falls
Increased risk of obesity and mental health issues

Black Panther
Vegetarian diet reduces obesity
Unknown risks of potion drinking

Black Widow
Childhood traumas increase risk of mental illnesses

Thor
He's a god

Which honey takes your fancy?

Al Ghaf Honey

The Al Ghaf tree is a local desert tree which bears the harsh summers with drought and high temperatures. From the rich flowers, bees that pollinate this tree can produce delicious red colour honey in June and July each year

Sidr Honey

The Sidr tree is an evergreen tree with long and strong forked branches. The blossom from this tree is called Yabyab, which provides rich food for bees to produce honey in October and November. This honey is the most expensive, but tastiest

Samar Honey

The Samar tree trunk, leaves and blossom contains Barm which is the secret of healing. You can enjoy the best types of honey from this tree every year in May and June. It is an historical witness to the life of the Emirati nation which represents the harsh desert and mountain environments

Eyasses squad

Charlie Preston (captain) – goal shooter/ goalkeeper (Dubai College)

Arushi Holt (vice-captain) – wing defence / centre (Jumeriah English Speaking School)  

Olivia Petricola (vice-captain) – centre / wing attack (Dubai English Speaking College)

Isabel Affley – goalkeeper / goal defence (Dubai English Speaking College)

Jemma Eley – goal attack / wing attack (Dubai College)

Alana Farrell-Morton – centre / wing / defence / wing attack (Nord Anglia International School)

Molly Fuller – goal attack / wing attack (Dubai College)

Caitlin Gowdy – goal defence / wing defence (Dubai English Speaking College)

Noorulain Hussain – goal defence / wing defence (Dubai College)

Zahra Hussain-Gillani – goal defence / goalkeeper (British School Al Khubairat)

Claire Janssen – goal shooter / goal attack (Jumeriah English Speaking School)         

Eliza Petricola – wing attack / centre (Dubai English Speaking College)

Cryopreservation: A timeline
  1. Keyhole surgery under general anaesthetic
  2. Ovarian tissue surgically removed
  3. Tissue processed in a high-tech facility
  4. Tissue re-implanted at a time of the patient’s choosing
  5. Full hormone production regained within 4-6 months
UAE currency: the story behind the money in your pockets
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Mageed Yahia, director of WFP in UAE: Coronavirus knows no borders, and neither should the response

Some of Darwish's last words

"They see their tomorrows slipping out of their reach. And though it seems to them that everything outside this reality is heaven, yet they do not want to go to that heaven. They stay, because they are afflicted with hope." - Mahmoud Darwish, to attendees of the Palestine Festival of Literature, 2008

His life in brief: Born in a village near Galilee, he lived in exile for most of his life and started writing poetry after high school. He was arrested several times by Israel for what were deemed to be inciteful poems. Most of his work focused on the love and yearning for his homeland, and he was regarded the Palestinian poet of resistance. Over the course of his life, he published more than 30 poetry collections and books of prose, with his work translated into more than 20 languages. Many of his poems were set to music by Arab composers, most significantly Marcel Khalife. Darwish died on August 9, 2008 after undergoing heart surgery in the United States. He was later buried in Ramallah where a shrine was erected in his honour.

How to come clean about financial infidelity
  • Be honest and transparent: It is always better to own up than be found out. Tell your partner everything they want to know. Show remorse. Inform them of the extent of the situation so they know what they are dealing with.
  • Work on yourself: Be honest with yourself and your partner and figure out why you did it. Don’t be ashamed to ask for professional help. 
  • Give it time: Like any breach of trust, it requires time to rebuild. So be consistent, communicate often and be patient with your partner and yourself.
  • Discuss your financial situation regularly: Ensure your spouse is involved in financial matters and decisions. Your ability to consistently follow through with what you say you are going to do when it comes to money can make all the difference in your partner’s willingness to trust you again.
  • Work on a plan to resolve the problem together: If there is a lot of debt, for example, create a budget and financial plan together and ensure your partner is fully informed, involved and supported. 

Carol Glynn, founder of Conscious Finance Coaching

Mercedes V250 Avantgarde specs

Engine: 2.0-litre in-line four-cylinder turbo

Gearbox: 7-speed automatic

Power: 211hp at 5,500rpm

Torque: 350Nm

Fuel economy, combined: 6.0 l/100 km

Price: Dh235,000

WHAT IS GRAPHENE?

It was discovered in 2004, when Russian-born Manchester scientists Andrei Geim and Kostya Novoselov were experimenting with sticky tape and graphite, the material used as lead in pencils.

Placing the tape on the graphite and peeling it, they managed to rip off thin flakes of carbon. In the beginning they got flakes consisting of many layers of graphene. But when they repeated the process many times, the flakes got thinner.

By separating the graphite fragments repeatedly, they managed to create flakes that were just one atom thick. Their experiment led to graphene being isolated for the very first time.

In 2010, Geim and Novoselov were awarded the Nobel Prize for Physics. 

The specs

Engine: 2.0-litre 4-cylturbo

Transmission: seven-speed DSG automatic

Power: 242bhp

Torque: 370Nm

Price: Dh136,814

MATCH INFO

Uefa Champions League semi-finals, first leg
Liverpool v Roma

When: April 24, 10.45pm kick-off (UAE)
Where: Anfield, Liverpool
Live: BeIN Sports HD
Second leg: May 2, Stadio Olimpico, Rome

UAE currency: the story behind the money in your pockets
While you're here
WHAT IS A BLACK HOLE?

1. Black holes are objects whose gravity is so strong not even light can escape their pull

2. They can be created when massive stars collapse under their own weight

3. Large black holes can also be formed when smaller ones collide and merge

4. The biggest black holes lurk at the centre of many galaxies, including our own

5. Astronomers believe that when the universe was very young, black holes affected how galaxies formed

Living in...

This article is part of a guide on where to live in the UAE. Our reporters will profile some of the country’s most desirable districts, provide an estimate of rental prices and introduce you to some of the residents who call each area home.

BIOSAFETY LABS SECURITY LEVELS

Biosafety Level 1

The lowest safety level. These labs work with viruses that are minimal risk to humans.

Hand washing is required on entry and exit and potentially infectious material decontaminated with bleach before thrown away.

Must have a lock. Access limited. Lab does not need to be isolated from other buildings.

Used as teaching spaces.

Study microorganisms such as Staphylococcus which causes food poisoning.

Biosafety Level 2

These labs deal with pathogens that can be harmful to people and the environment such as Hepatitis, HIV and salmonella.

Working in Level 2 requires special training in handling pathogenic agents.

Extra safety and security precautions are taken in addition to those at Level 1

Biosafety Level 3

These labs contain material that can be lethal if inhaled. This includes SARS coronavirus, MERS, and yellow fever.

Significant extra precautions are taken with staff given specific immunisations when dealing with certain diseases.

Infectious material is examined in a biological safety cabinet.

Personnel must wear protective gowns that must be discarded or decontaminated after use.

Strict safety and handling procedures are in place. There must be double entrances to the building and they must contain self-closing doors to reduce risk of pathogen aerosols escaping.

Windows must be sealed. Air from must be filtered before it can be recirculated.

Biosafety Level 4

The highest level for biosafety precautions. Scientist work with highly dangerous diseases that have no vaccine or cure.

All material must be decontaminated.

Personnel must wear a positive pressure suit for protection. On leaving the lab this must pass through decontamination shower before they have a personal shower.

Entry is severely restricted to trained and authorised personnel. All entries are recorded.

Entrance must be via airlocks.