AstraZeneca’s Covid vaccine: should you be worried about side effects?


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Several European countries suspended use of the AstraZeneca-Oxford Covid-19 vaccine.

Temporary bans were put in place after a small number of people who received the drug suffered blood clots.

We look at the key questions surrounding the situation.

Should people be worried about taking AstraZeneca’s vaccine?

No. Many scientists criticised European countries for acting too hastily in suspending the vaccine while the pandemic is ongoing.

Health experts said the number of blood clots reported in vaccinated people is no higher than in the general population, and that there is no evidence to link the vaccine directly to blood clotting.

“I think it is very clear that the benefits of being vaccinated at the moment … outweigh the possible concern over this rather rare type of blood clot,” Prof Peter Openshaw from Imperial College London told the BBC.

“It really is a completely one-sided argument statistically that we need to be vaccinating.”

Dr Simon Clarke, a microbiologist at the University of Reading, said it was reckless to stop using the vaccine.

“I keep hearing the phrase 'abundance of caution' being used in reference to countries pausing rollout of the Oxford vaccine, but is it really caution?” he said.

Prof Stephen Evans from the London School of Hygiene and Tropical Medicine said some European countries were taking a “super-cautious approach based on some isolated reports”.

"The problem with spontaneous reports of suspected adverse reactions to a vaccine is the enormous difficulty of distinguishing a causal effect from a coincidence," he said.

Why did European countries suspend AstraZeneca’s vaccine?

A small number of blood-clotting incidents were reported in people who had received the vaccine made by AstraZeneca-Oxford.

Austria suspended a batch of the drug on March 9 while authorities investigated a death from a pulmonary embolism, an acute lung disease caused by a dislodged blood clot.

A notice of suspension for AstraZeneca's Covid-19 vaccine in Rome. EPA
A notice of suspension for AstraZeneca's Covid-19 vaccine in Rome. EPA

Denmark was next after a 60-year-old woman died from a blood clot after she was given a dose of AstraZeneca's Covid vaccine from the same batch used in Austria.

Deaths from blood clots were also reported in Norway and Italy.

The medicines regulator said there were 30 cases of "thromboembolic events" among five million people in Europe who had received at least one dose of the vaccine.

French immunologist Alain Fischer, who heads a vaccination advisory board, said the cases caused alarm.

"There were a few very unusual and troubling cases which justify this pause and the analysis," Prof Fischer told France Inter radio.

"It's not lost time."

Which European countries suspended AstraZeneca’s vaccine?

Germany, France, Italy and Spain on Monday suspended AstraZeneca's Covid vaccinations, joining Ireland, Denmark, Norway, Bulgaria and Iceland.

Sweden on Tuesday became the latest country to halt distribution.

Austria suspended vaccinations from one batch of the drug, as did Estonia, Latvia, Luxembourg, Lithuania and Romania.

A deserted vaccination centre in Germany after the country paused inoculations with the AstraZeneca-Oxford Covid-19 drug. AP
A deserted vaccination centre in Germany after the country paused inoculations with the AstraZeneca-Oxford Covid-19 drug. AP

How did the European Medical Association react?

The EU's medicines regulator said on Tuesday it was "firmly convinced" that the benefits of AstraZeneca's Covid shot outweighed potential risks, insisting there was no evidence linking the vaccine to blood clots.

"We are still firmly convinced that the benefits of the AstraZeneca vaccine in preventing Covid-19 with its associated risk of hospitalisation and death outweigh the risk of these side effects," EMA executive director Emer Cooke said.

"At present there is no indication that vaccination caused these conditions".

Scientists have widely criticised European countries for suspending the shot, saying there is not enough evidence linking it to blood clotting. Reuters
Scientists have widely criticised European countries for suspending the shot, saying there is not enough evidence linking it to blood clotting. Reuters

Ms Cooke said that the regulator was "looking at adverse events associated with all vaccines".

How did British authorities react?

Authorities in Britain see no evidence of more frequent blood clots among those inoculated with the vaccine.

The country has administered more than 11 million AstraZeneca-Oxford doses.

The UK’s Healthcare Products Regulatory Agency said people should continue to receive their Covid-19 vaccines.

“We are closely reviewing reports but the evidence available does not suggest the vaccine is the cause,” MHRA safety lead Dr Phil Bryan said.

“Blood clots can occur naturally and are not uncommon … the number of blood clots reported after having the vaccine is not greater than the number that would have occurred naturally in the vaccinated population.”

Prime Minister Boris Johnson hailed the effectiveness of the British-made vaccine and said it demonstrated the country's worldwide influence.

"That vaccine is safe and works extremely well, and now, only six months later, it is being made in multiple places from India to the US, as well as Britain, and it is being used around the world," he wrote in The Times.

What is the next step?

The EMA’s safety committee reviewed blood clot data on Tuesday and an extraordinary meeting was called for Thursday to consider whether any action should be taken.

If a strong association is found with vaccination, the regulator could put procedures in place to avoid similar problems occurring.

Several countries said they would lift the ban on AstraZeneca vaccines if the committee decided on Thursday decided against further action.

What did AstraZeneca say?

AstraZeneca said 15 events of deep-vein thrombosis – a blood clot in a vein – and 22 events of pulmonary embolism – when a blood clot entersthe lungs – were reported among those vaccinated in the UK and EU.

The company said these figures were "much lower than would be expected to occur naturally in a general population of this size and is similar across other licensed Covid-19 vaccines".

Has the EU had problems with AstraZeneca before?

The EU was embroiled in a major dispute with AstraZeneca this year after the pharmaceutical company said it would reduce deliveries to the bloc owing to a shortage of doses.

On March 5, Italy used the bloc’s transparency mechanism to block a shipment of vaccines made by AstraZeneca bound for Australia.

How will the ban affect Europe’s struggling vaccination drive?

The temporary bans came as Europe’s inoculation campaign was beginning to gather pace after a difficult start.

As well as supply shortages, some European nations experienced hesitancy, with people reluctant to take the AstraZeneca shot.

The drug was labelled “quasi-ineffective” by French President Emmanuel Macron.

German and French regulators added to the problem after recommending the vaccine for people aged under 65, citing a lack of safety data in vaccinated groups.

Those decisions were reversed but the damage was already done, with vaccine centres stocked with doses from AstraZeneca pictured empty.

Prof Openshaw said the latest news was likely to further damage the drug’s reputation in Europe.

“I think it is a disaster for the vaccination uptake in Europe, which is already on slightly unsteady ground in some countries,” he said.

UAE currency: the story behind the money in your pockets
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UAE currency: the story behind the money in your pockets
The specs: 2018 Mercedes-AMG C63 S Cabriolet

Price, base: Dh429,090

Engine 4.0-litre twin-turbo V8

Transmission Seven-speed automatic

Power 510hp @ 5,500rpm

Torque 700Nm @ 1,750rpm

Fuel economy, combined 9.2L / 100km

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Karnataka Tuskers 110-5 (10 ovs)

Tharanga 48, Shafiq 34, Rampaul 2-16

Delhi Bulls 91-8 (10 ovs)

Mathews 31, Rimmington 3-28

Karnataka Tuskers win by 19 runs

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The specs
  • Engine: 3.9-litre twin-turbo V8
  • Power: 640hp
  • Torque: 760nm
  • On sale: 2026
  • Price: Not announced yet
What is the Supreme Petroleum Council?

The Abu Dhabi Supreme Petroleum Council was established in 1988 and is the highest governing body in Abu Dhabi’s oil and gas industry. The council formulates, oversees and executes the emirate’s petroleum-related policies. It also approves the allocation of capital spending across state-owned Adnoc’s upstream, downstream and midstream operations and functions as the company’s board of directors. The SPC’s mandate is also required for auctioning oil and gas concessions in Abu Dhabi and for awarding blocks to international oil companies. The council is chaired by Sheikh Khalifa, the President and Ruler of Abu Dhabi while Sheikh Mohamed bin Zayed, Abu Dhabi’s Crown Prince and Deputy Supreme Commander of the Armed Forces, is the vice chairman.

Sole survivors
  • Cecelia Crocker was on board Northwest Airlines Flight 255 in 1987 when it crashed in Detroit, killing 154 people, including her parents and brother. The plane had hit a light pole on take off
  • George Lamson Jr, from Minnesota, was on a Galaxy Airlines flight that crashed in Reno in 1985, killing 68 people. His entire seat was launched out of the plane
  • Bahia Bakari, then 12, survived when a Yemenia Airways flight crashed near the Comoros in 2009, killing 152. She was found clinging to wreckage after floating in the ocean for 13 hours.
  • Jim Polehinke was the co-pilot and sole survivor of a 2006 Comair flight that crashed in Lexington, Kentucky, killing 49.
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The specs: 2019 BMW X4

Price, base / as tested: Dh276,675 / Dh346,800

Engine: 3.0-litre turbocharged in-line six-cylinder

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­9: Annual growth in philanthropy

The specs

Engine: 3.8-litre twin-turbo V8

Power: 611bhp

Torque: 620Nm

Transmission: seven-speed automatic

Price: upon application

On sale: now

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Liverpool 2 (Van Dijk 18', 24')

Brighton 1 (Dunk 79')

Red card: Alisson (Liverpool)

Tributes from the UAE's personal finance community

• Sebastien Aguilar, who heads SimplyFI.org, a non-profit community where people learn to invest Bogleheads’ style

“It is thanks to Jack Bogle’s work that this community exists and thanks to his work that many investors now get the full benefits of long term, buy and hold stock market investing.

Compared to the industry, investing using the common sense approach of a Boglehead saves a lot in costs and guarantees higher returns than the average actively managed fund over the long term. 

From a personal perspective, learning how to invest using Bogle’s approach was a turning point in my life. I quickly realised there was no point chasing returns and paying expensive advisers or platforms. Once money is taken care off, you can work on what truly matters, such as family, relationships or other projects. I owe Jack Bogle for that.”

• Sam Instone, director of financial advisory firm AES International

"Thought to have saved investors over a trillion dollars, Jack Bogle’s ideas truly changed the way the world invests. Shaped by his own personal experiences, his philosophy and basic rules for investors challenged the status quo of a self-interested global industry and eventually prevailed.  Loathed by many big companies and commission-driven salespeople, he has transformed the way well-informed investors and professional advisers make decisions."

• Demos Kyprianou, a board member of SimplyFI.org

"Jack Bogle for me was a rebel, a revolutionary who changed the industry and gave the little guy like me, a chance. He was also a mentor who inspired me to take the leap and take control of my own finances."

• Steve Cronin, founder of DeadSimpleSaving.com

"Obsessed with reducing fees, Jack Bogle structured Vanguard to be owned by its clients – that way the priority would be fee minimisation for clients rather than profit maximisation for the company.

His real gift to us has been the ability to invest in the stock market (buy and hold for the long term) rather than be forced to speculate (try to make profits in the shorter term) or even worse have others speculate on our behalf.

Bogle has given countless investors the ability to get on with their life while growing their wealth in the background as fast as possible. The Financial Independence movement would barely exist without this."

• Zach Holz, who blogs about financial independence at The Happiest Teacher

"Jack Bogle was one of the greatest forces for wealth democratisation the world has ever seen.  He allowed people a way to be free from the parasitical "financial advisers" whose only real concern are the fat fees they get from selling you over-complicated "products" that have caused millions of people all around the world real harm.”

• Tuan Phan, a board member of SimplyFI.org

"In an industry that’s synonymous with greed, Jack Bogle was a lone wolf, swimming against the tide. When others were incentivised to enrich themselves, he stood by the ‘fiduciary’ standard – something that is badly needed in the financial industry of the UAE."

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The specs

Engine: 1.5-litre 4-cyl turbo

Power: 194hp at 5,600rpm

Torque: 275Nm from 2,000-4,000rpm

Transmission: 6-speed auto

Price: from Dh155,000

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Engine: Electric single motor (96kW), twin motor (106kW) and twin motor performance (106kW)

Power: 333hp, 449hp, 680hp

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On sale: Later in 2025 or early 2026, depending on region

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From Conquest to Deportation

Jeronim Perovic, Hurst

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Global state-owned investor ranking by size

1.

United States

2.

China

3.

UAE

4.

Japan

5

Norway

6.

Canada

7.

Singapore

8.

Australia

9.

Saudi Arabia

10.

South Korea

Company profile

Name: The Concept

Founders: Yadhushan Mahendran, Maria Sobh and Muhammad Rijal

Based: Abu Dhabi

Founded: 2017

Number of employees: 7

Sector: Aviation and space industry

Funding: $250,000

Future plans: Looking to raise $1 million investment to boost expansion and develop new products

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1. Fasting 

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2. Stefan Kueng (Switzerland / BMC Racing) 17

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9. Marcel Kittel (Germany / Quick-Step) 7

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Prophets of Rage

(Fantasy Records)

Where to donate in the UAE

The Emirates Charity Portal

You can donate to several registered charities through a “donation catalogue”. The use of the donation is quite specific, such as buying a fan for a poor family in Niger for Dh130.

The General Authority of Islamic Affairs & Endowments

The site has an e-donation service accepting debit card, credit card or e-Dirham, an electronic payment tool developed by the Ministry of Finance and First Abu Dhabi Bank.

Al Noor Special Needs Centre

You can donate online or order Smiles n’ Stuff products handcrafted by Al Noor students. The centre publishes a wish list of extras needed, starting at Dh500.

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Dar Al Ber Society, which has charity projects in 39 countries, accept cash payments, money transfers or SMS donations. Its donation hotline is 800-79.

Dubai Cares

Dubai Cares provides several options for individuals and companies to donate, including online, through banks, at retail outlets, via phone and by purchasing Dubai Cares branded merchandise. It is currently running a campaign called Bookings 2030, which allows people to help change the future of six underprivileged children and young people.

Emirates Airline Foundation

Those who travel on Emirates have undoubtedly seen the little donation envelopes in the seat pockets. But the foundation also accepts donations online and in the form of Skywards Miles. Donated miles are used to sponsor travel for doctors, surgeons, engineers and other professionals volunteering on humanitarian missions around the world.

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On the Emirates Red Crescent website you can choose between 35 different purposes for your donation, such as providing food for fasters, supporting debtors and contributing to a refugee women fund. It also has a list of bank accounts for each donation type.

Gulf for Good

Gulf for Good raises funds for partner charity projects through challenges, like climbing Kilimanjaro and cycling through Thailand. This year’s projects are in partnership with Street Child Nepal, Larchfield Kids, the Foundation for African Empowerment and SOS Children's Villages. Since 2001, the organisation has raised more than $3.5 million (Dh12.8m) in support of over 50 children’s charities.

Noor Dubai Foundation

Sheikh Mohammed bin Rashid Al Maktoum launched the Noor Dubai Foundation a decade ago with the aim of eliminating all forms of preventable blindness globally. You can donate Dh50 to support mobile eye camps by texting the word “Noor” to 4565 (Etisalat) or 4849 (du).