Could camel milk be key to developing new drugs to combat diabetes?


Gillian Duncan
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Researchers in the UAE have shed new light on why camel milk is beneficial for people with diabetes, in a study which could boost future efforts to manage the disease.

The drink's positive effects on blood sugar are well established – including reducing fasting levels, lowering insulin resistance and improving lipid profiles among diabetic patients.

A UAE study sought to better understand the Middle East staple's role in fighting diabetes by examining at a molecular level to see how cells react.

Their work showed how bioactive peptides – the building blocks of proteins – extracted from camel milk, have positive effects on the human insulin receptor and glucose transport in cells.

This moves research one step further in the identification and characterization of the anti-diabetic agent contained in camel milk

The researchers said the findings are highly promising and may even lead to a breakthrough in the fight against diabetes using drugs developed from camel milk.

"Camel milk's therapeutic properties against diseases such as diabetes and cancer have been widely studied and reviewed in the past decade," wrote the researchers in the Journal of Dairy Science.

The study, entitled Molecular Basis of the Antidiabetic Properties of Camel Milk Through Profiling of its Bioactive Peptides on DPP-IV and Insulin Receptor Activity was led by Dr Mohammed Ayoub's lab from the Department of Biology at United Arab Emirates University and Dr Sajid Maqsood's lab from the Department of Food Science at United Arab Emirates University, with support from Zayed Centre for Health Sciences.

It is "widely noted that camel milk consumption is beneficial in reducing the dose of insulin needed to induce glycemic control and improves fasting blood glucose", they wrote.

“This moves research one step further in the identification and characterisation of the anti-diabetic agent contained in camel milk and opens interesting perspectives for the development of new anti-diabetic drugs from camel milk products.”

Dr Mohammed Ayoub and his team at UAE University have played an integral role in the research on the health benefits of camel milk. Courtesy: Wam
Dr Mohammed Ayoub and his team at UAE University have played an integral role in the research on the health benefits of camel milk. Courtesy: Wam

Around one in five people in the UAE suffer from diabetes, a condition that can cause multiple serious health problems, such as heart disease and damage to organs, including the eyes and kidneys.

Experts expect the number of people with the condition to double within the next 30 years, so new treatments are crucial to managing the condition.

Compared to other milk, camel milk contains less sugar and cholesterol, and has a higher mineral content.

It has also been recognised for having “potent antimicrobial and anti-inflammatory properties,” and may protect against the development of cancer.

In 2019, researchers in Jordan embarked on a study to examine the effect of camel milk on the development of colorectal cancer in mice.

During the study, 30 mice were given an injection and fed a substance that promoted the development of colorectal cancer.

Some were also given camel milk whey – the watery liquid left behind after curd is removed – another group was given cow milk whey, and a further group received neither.

Six out of 10 mice not given any whey were found to have tumours in their colon, while six out of eight of those fed cow milk whey had tumours.

Among the mice that had been given camel milk whey, however, just one out of eight had tumours.

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The Sinopharm vaccine was created using techniques that have been around for decades. 

“This is an inactivated vaccine. Simply what it means is that the virus is taken, cultured and inactivated," said Dr Nawal Al Kaabi, chair of the UAE's National Covid-19 Clinical Management Committee.

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Farage on Muslim Brotherhood

Nigel Farage told Reform's annual conference that the party will proscribe the Muslim Brotherhood if he becomes Prime Minister.
"We will stop dangerous organisations with links to terrorism operating in our country," he said. "Quite why we've been so gutless about this – both Labour and Conservative – I don't know.
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Among the former diplomat's findings was an assessment that “the use of extreme violence in the pursuit of the perfect Islamic society” has “never been institutionally disowned” by the movement.
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Key findings of Jenkins report
  • Founder of the Muslim Brotherhood, Hassan al Banna, "accepted the political utility of violence"
  • Views of key Muslim Brotherhood ideologue, Sayyid Qutb, have “consistently been understood” as permitting “the use of extreme violence in the pursuit of the perfect Islamic society” and “never been institutionally disowned” by the movement.
  • Muslim Brotherhood at all levels has repeatedly defended Hamas attacks against Israel, including the use of suicide bombers and the killing of civilians.
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VEZEETA PROFILE

Date started: 2012

Founder: Amir Barsoum

Based: Dubai, UAE

Sector: HealthTech / MedTech

Size: 300 employees

Funding: $22.6 million (as of September 2018)

Investors: Technology Development Fund, Silicon Badia, Beco Capital, Vostok New Ventures, Endeavour Catalyst, Crescent Enterprises’ CE-Ventures, Saudi Technology Ventures and IFC

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The smuggler

Eldarir had arrived at JFK in January 2020 with three suitcases, containing goods he valued at $300, when he was directed to a search area.
Officers found 41 gold artefacts among the bags, including amulets from a funerary set which prepared the deceased for the afterlife.
Also found was a cartouche of a Ptolemaic king on a relief that was originally part of a royal building or temple. 
The largest single group of items found in Eldarir’s cases were 400 shabtis, or figurines.

Khouli conviction

Khouli smuggled items into the US by making false declarations to customs about the country of origin and value of the items.
According to Immigration and Customs Enforcement, he provided “false provenances which stated that [two] Egyptian antiquities were part of a collection assembled by Khouli's father in Israel in the 1960s” when in fact “Khouli acquired the Egyptian antiquities from other dealers”.
He was sentenced to one year of probation, six months of home confinement and 200 hours of community service in 2012 after admitting buying and smuggling Egyptian antiquities, including coffins, funerary boats and limestone figures.

For sale

A number of other items said to come from the collection of Ezeldeen Taha Eldarir are currently or recently for sale.
Their provenance is described in near identical terms as the British Museum shabti: bought from Salahaddin Sirmali, "authenticated and appraised" by Hossen Rashed, then imported to the US in 1948.

- An Egyptian Mummy mask dating from 700BC-30BC, is on offer for £11,807 ($15,275) online by a seller in Mexico

- A coffin lid dating back to 664BC-332BC was offered for sale by a Colorado-based art dealer, with a starting price of $65,000

- A shabti that was on sale through a Chicago-based coin dealer, dating from 1567BC-1085BC, is up for $1,950

Specs
Engine: Electric motor generating 54.2kWh (Cooper SE and Aceman SE), 64.6kW (Countryman All4 SE)
Power: 218hp (Cooper and Aceman), 313hp (Countryman)
Torque: 330Nm (Cooper and Aceman), 494Nm (Countryman)
On sale: Now
Price: From Dh158,000 (Cooper), Dh168,000 (Aceman), Dh190,000 (Countryman)
MATCH INFO

Manchester City 3 (Sterling 46', De Bruyne 65', Gundogan 70')

Aston Villa 0

Red card: Fernandinho (Manchester City)

Man of the Match: Raheem Sterling (Manchester City)

The five pillars of Islam
UAE central contracts

Full time contracts

Rohan Mustafa, Ahmed Raza, Mohammed Usman, Chirag Suri, Mohammed Boota, Sultan Ahmed, Zahoor Khan, Junaid Siddique, Waheed Ahmed, Zawar Farid

Part time contracts

Aryan Lakra, Ansh Tandon, Karthik Meiyappan, Rahul Bhatia, Alishan Sharafu, CP Rizwaan, Basil Hameed, Matiullah, Fahad Nawaz, Sanchit Sharma

Federer's 11 Wimbledon finals

2003 Beat Mark Philippoussis

2004 Beat Andy Roddick

2005 Beat Andy Roddick

2006 Beat Rafael Nadal

2007 Beat Rafael Nadal

2008 Lost to Rafael Nadal

2009 Beat Andy Roddick

2012 Beat Andy Murray

2014 Lost to Novak Djokovic

2015 Lost to Novak Djokovic

2017 Beat Marin Cilic