Abu Dhabi and Australia have signed an agreement to grow the global RNA ecosystem and develop future Covid-19 treatments.
The agreement was signed by Dr Jamal Al Kaabi, Undersecretary of Department of Health – Abu Dhabi and Michael Kapel, chief executive of mRNA Victoria, an Australian government initiative.
The UAE and Australia will identify areas of interest related to mRNA research, initiate collaborations and knowledge exchange and identify early-stage research investment opportunities.
mRNA technology made headlines when the Pfizer-BioNTech and Moderna Covid-19 vaccines were approved for use, first in the US, and then globally, during the pandemic.
With the signing of this, we look forward to seeing advancements in mRNA-based therapeutics research and strengthening the capabilities of the international healthcare system
Dr Jamal Al Kaabi,
Department of Health – Abu Dhabi
Many vaccines put a weakened or inactivated germ into our bodies to trigger an immune response.
But with mRNA technology, scientists tackle disease by borrowing the body’s natural protein-building software.
The idea is to use this software, or messenger RNA (mRNA), to create exact replicas of a known enemy such as the distinctive spike of the novel coronavirus.
That way, the immune system learns to recognise its foe and will be ready for battle when it meets the real thing.
Experts believe mRNA could change the future of medicine and healthcare.
The collaboration will explore clinical trial opportunities and areas for private sector investment in Abu Dhabi and Victoria state in Australia.
With a focus on the development of the RNA ecosystem, both sides will be able to identify prospective partners and collaborate with organisations seeking to develop and licence RNA-based therapeutics and treatments.
A steering committee of members from the Department of Health and mRNA Victoria will be set up to ensure alignment and effective execution of projects.
“We are always open to forward-thinking and innovative collaborations with leading global partners, such as the state of Victoria," said Dr Al Kaabi.
"With the signing of this, we look forward to seeing advancements in mRNA-based therapeutics research and strengthening the capabilities of the international healthcare system so that we are better prepared for future pandemics and health crises."
Jaala Pulford, Minister for Innovation, Medical Research and the Digital Economy, in the government of Victoria said: “This agreement signifies a global collaboration to share knowledge, information and expertise within the ecosystem supporting supply chains research and development for pre and clinical research, commercialisation and manufacturing investments.”
In the past five years, Abu Dhabi doubled its research capabilities and developed several scientific, clinical and research programmes. These exceeded the number of projects carried out during the previous five years.
The Department of Health also launched the Covid-19 Research Registry, a platform that supports scientific research and discoveries related to the virus and disease. The registry has received 386 scientific papers. Of these, 340 papers have been approved and 46 were published.
What is RNA?
RNA, or ribonucleic acid, is a molecule that plays a central role in the function of genes.
After the success of mRNA Covid-19 vaccines, experts believe that the technology can be used to unlock the root causes of neurodegenerative diseases such as Alzheimer’s.
Diseases including cancer, osteoporosis, diabetes and cystic fibrosis could all be targeted by mRNA-based treatments or preventive vaccines.
mRNA and other forms of RNA, such as siRNA, miRNA and gRNA, also have huge potential in medicine beyond vaccines.
It can also be used in the biotechnology and agricultural sectors.
How does it work?
Although mRNA can be made artificially, it is not a human invention, because it plays a central role in the production of proteins from an organism’s genes.
Consisting of a single strand of ribonucleic acid (RNA), mRNA is where genes (which in people are made from deoxyribonucleic acid or DNA) are copied inside the nucleus of cells.
The mRNA travels into the liquid area outside the nucleus, the cytoplasm, where, in a process called translation, it codes for the production of a protein.
The sequence of amino acids (protein building blocks) that make up this protein is determined by the sequence of the base pairs or repeating units of the mRNA.
When mRNA is administered as a vaccine or other therapeutic substance, it too ends up in cells, where translation takes place and proteins are produced.
With Covid-19 vaccines, these proteins are coronavirus spike proteins, the immune response to which offers protection if the person is subsequently infected with the virus.
Bundesliga fixtures
Saturday, May 16 (kick-offs UAE time)
Borussia Dortmund v Schalke (4.30pm)
RB Leipzig v Freiburg (4.30pm)
Hoffenheim v Hertha Berlin (4.30pm)
Fortuna Dusseldorf v Paderborn (4.30pm)
Augsburg v Wolfsburg (4.30pm)
Eintracht Frankfurt v Borussia Monchengladbach (7.30pm)
Sunday, May 17
Cologne v Mainz (4.30pm),
Union Berlin v Bayern Munich (7pm)
Monday, May 18
Werder Bremen v Bayer Leverkusen (9.30pm)
Benefits of first-time home buyers' scheme
- Priority access to new homes from participating developers
- Discounts on sales price of off-plan units
- Flexible payment plans from developers
- Mortgages with better interest rates, faster approval times and reduced fees
- DLD registration fee can be paid through banks or credit cards at zero interest rates
BRIEF SCORES
England 353 and 313-8 dec
(B Stokes 112, A Cook 88; M Morkel 3-70, K Rabada 3-85)
(J Bairstow 63, T Westley 59, J Root 50; K Maharaj 3-50)
South Africa 175 and 252
(T Bavuma 52; T Roland-Jones 5-57, J Anderson 3-25)
(D Elgar 136; M Ali 4-45, T Roland-Jones 3-72)
Result: England won by 239 runs
England lead four-match series 2-1
Results
2pm: Maiden (TB) Dh60,000 (Dirt) 1,200m, Winner: Mouheeb, Tom Marquand (jockey), Nicholas Bachalard (trainer)
2.30pm: Handicap (TB) Dh68,000 (D) 1,200m, Winner: Honourable Justice, Royston Ffrench, Salem bin Ghadayer
3pm: Handicap (TB) Dh84,000 (D) 1,200m, Winner: Dahawi, Antonio Fresu, Musabah Al Muhairi
3.30pm: Conditions (TB) Dh100,000 (D) 1,200m, Winner: Dark Silver, Fernando Jara, Ahmad bin Harmash
4pm: Maiden (TB) Dh60,000 (D) 1,600m, Winner: Dark Of Night. Antonio Fresu, Al Muhairi.
4.30pm: Handicap (TB) Dh68,000 (D) 1,600m, Winner: Habah, Pat Dobbs, Doug Watson
ELIO
Starring: Yonas Kibreab, Zoe Saldana, Brad Garrett
Directors: Madeline Sharafian, Domee Shi, Adrian Molina
Rating: 4/5
Tell-tale signs of burnout
- loss of confidence and appetite
- irritability and emotional outbursts
- sadness
- persistent physical ailments such as headaches, frequent infections and fatigue
- substance abuse, such as smoking or drinking more
- impaired judgement
- excessive and continuous worrying
- irregular sleep patterns
Tips to help overcome burnout
Acknowledge how you are feeling by listening to your warning signs. Set boundaries and learn to say ‘no’
Do activities that you want to do as well as things you have to do
Undertake at least 30 minutes of exercise per day. It releases an abundance of feel-good hormones
Find your form of relaxation and make time for it each day e.g. soothing music, reading or mindful meditation
Sleep and wake at the same time every day, even if your sleep pattern was disrupted. Without enough sleep condition such as stress, anxiety and depression can thrive.
Specs
Engine: Dual-motor all-wheel-drive electric
Range: Up to 610km
Power: 905hp
Torque: 985Nm
Price: From Dh439,000
Available: Now
PAKISTAN v SRI LANKA
Twenty20 International series
Thu Oct 26, 1st T20I, Abu Dhabi
Fri Oct 27, 2nd T20I, Abu Dhabi
Sun Oct 29, 3rd T20I, Lahore
Tickets are available at www.q-tickets.com
Sole survivors
- Cecelia Crocker was on board Northwest Airlines Flight 255 in 1987 when it crashed in Detroit, killing 154 people, including her parents and brother. The plane had hit a light pole on take off
- George Lamson Jr, from Minnesota, was on a Galaxy Airlines flight that crashed in Reno in 1985, killing 68 people. His entire seat was launched out of the plane
- Bahia Bakari, then 12, survived when a Yemenia Airways flight crashed near the Comoros in 2009, killing 152. She was found clinging to wreckage after floating in the ocean for 13 hours.
- Jim Polehinke was the co-pilot and sole survivor of a 2006 Comair flight that crashed in Lexington, Kentucky, killing 49.
Dates for the diary
To mark Bodytree’s 10th anniversary, the coming season will be filled with celebratory activities:
- September 21 Anyone interested in becoming a certified yoga instructor can sign up for a 250-hour course in Yoga Teacher Training with Jacquelene Sadek. It begins on September 21 and will take place over the course of six weekends.
- October 18 to 21 International yoga instructor, Yogi Nora, will be visiting Bodytree and offering classes.
- October 26 to November 4 International pilates instructor Courtney Miller will be on hand at the studio, offering classes.
- November 9 Bodytree is hosting a party to celebrate turning 10, and everyone is invited. Expect a day full of free classes on the grounds of the studio.
- December 11 Yogeswari, an advanced certified Jivamukti teacher, will be visiting the studio.
- February 2, 2018 Bodytree will host its 4th annual yoga market.
The specs
- Engine: 3.9-litre twin-turbo V8
- Power: 640hp
- Torque: 760nm
- On sale: 2026
- Price: Not announced yet
The biog
Favourite car: Ferrari
Likes the colour: Black
Best movie: Avatar
Academic qualifications: Bachelor’s degree in media production from the Higher Colleges of Technology and diploma in production from the New York Film Academy
World Cup final
Who: France v Croatia
When: Sunday, July 15, 7pm (UAE)
TV: Game will be shown live on BeIN Sports for viewers in the Mena region
Specs
Engine: 51.5kW electric motor
Range: 400km
Power: 134bhp
Torque: 175Nm
Price: From Dh98,800
Available: Now
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Infiniti QX80 specs
Engine: twin-turbocharged 3.5-liter V6
Power: 450hp
Torque: 700Nm
Price: From Dh450,000, Autograph model from Dh510,000
Available: Now
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The BIO
Favourite piece of music: Verdi’s Requiem. It’s awe-inspiring.
Biggest inspiration: My father, as I grew up in a house where music was constantly played on a wind-up gramophone. I had amazing music teachers in primary and secondary school who inspired me to take my music further. They encouraged me to take up music as a profession and I follow in their footsteps, encouraging others to do the same.
Favourite book: Ian McEwan’s Atonement – the ending alone knocked me for six.
Favourite holiday destination: Italy - music and opera is so much part of the life there. I love it.
UAE currency: the story behind the money in your pockets
Four motivational quotes from Alicia's Dubai talk
“The only thing we need is to know that we have faith. Faith and hope in our own dreams. The belief that, when we keep going we’re going to find our way. That’s all we got.”
“Sometimes we try so hard to keep things inside. We try so hard to pretend it’s not really bothering us. In some ways, that hurts us more. You don’t realise how dishonest you are with yourself sometimes, but I realised that if I spoke it, I could let it go.”
“One good thing is to know you’re not the only one going through it. You’re not the only one trying to find your way, trying to find yourself, trying to find amazing energy, trying to find a light. Show all of yourself. Show every nuance. All of your magic. All of your colours. Be true to that. You can be unafraid.”
“It’s time to stop holding back. It’s time to do it on your terms. It’s time to shine in the most unbelievable way. It’s time to let go of negativity and find your tribe, find those people that lift you up, because everybody else is just in your way.”
More from Rashmee Roshan Lall
ESSENTIALS
The flights
Emirates flies from Dubai to Phnom Penh via Yangon from Dh2,700 return including taxes. Cambodia Bayon Airlines and Cambodia Angkor Air offer return flights from Phnom Penh to Siem Reap from Dh250 return including taxes. The flight takes about 45 minutes.
The hotels
Rooms at the Raffles Le Royal in Phnom Penh cost from $225 (Dh826) per night including taxes. Rooms at the Grand Hotel d'Angkor cost from $261 (Dh960) per night including taxes.
The tours
A cyclo architecture tour of Phnom Penh costs from $20 (Dh75) per person for about three hours, with Khmer Architecture Tours. Tailor-made tours of all of Cambodia, or sites like Angkor alone, can be arranged by About Asia Travel. Emirates Holidays also offers packages.
COMPANY PROFILE
● Company: Bidzi
● Started: 2024
● Founders: Akshay Dosaj and Asif Rashid
● Based: Dubai, UAE
● Industry: M&A
● Funding size: Bootstrapped
● No of employees: Nine
Company%20profile
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The biog
Title: General Practitioner with a speciality in cardiology
Previous jobs: Worked in well-known hospitals Jaslok and Breach Candy in Mumbai, India
Education: Medical degree from the Government Medical College in Nagpur
How it all began: opened his first clinic in Ajman in 1993
Family: a 90-year-old mother, wife and two daughters
Remembers a time when medicines from India were purchased per kilo
The White Lotus: Season three
Creator: Mike White
Starring: Walton Goggins, Jason Isaacs, Natasha Rothwell
Rating: 4.5/5
