An at-home DNA test could help doctors see early signs of colorectal cancer.
An at-home DNA test could help doctors see early signs of colorectal cancer.
An at-home DNA test could help doctors see early signs of colorectal cancer.
An at-home DNA test could help doctors see early signs of colorectal cancer.

UAE home cancer test aims to boost early detection and save lives


Nick Webster
  • English
  • Arabic

A home DNA testing kit set to be made available in the UAE could boost early detection rates for one of the most deadly but treatable types of cancer.

Scientists have developed a home stool test to detect early signs of colorectal cancer. The test uses technology similar to that of a Covid-19 PCR test.

German company Mainz Biomed said its ColoAlert test had a sensitivity and specificity rate comparable to a colonoscopy carried out as a hospital.

A clinical test in Germany found that ColoAlert has a sensitivity rate of 85 per cent and specificity rate of 92 per cent.

Figures from the International Agency for Research on Cancer at the World Health Organisation showed colorectal cancer was the second most common type in 2020, accounting for 10.6 per cent of all cases in the UAE.

A DNA test such as the ColoAlert in the UAE is a very efficient form of screening, taking into consideration cost effectiveness and better sensitivity
Dr Mahesh Rama

Doctors suggest an at-home test would encourage more people to perform checks on themselves to catch initial signs of colorectal cancer and seek earlier treatment that would lead to better survival rates.

Kits will be made available through the Dante Labs Genomics e-commerce site in Silicon Oasis in Dubai from June 8, with customers able to purchase tests online and samples collected and results returned within days.

Early detection boosts survival rates

“Patients diagnosed at a localised stage have a much higher survival rate compared with those who have metastatic spread of advanced cancer at the time of diagnosis,” said Dr Mahesh Rama Varma, a gastroenterologist at NMC Royal Hospital in Dubai.

“Early detection is the key to the prevention of advanced cancers.

“Types of tests for colorectal cancer screening include stool-based testing to detect either haemoglobin in the blood that may be coming from a lesion or DNA alterations suggestive of malignancy.

“Then there are the so called invasive tests, a colonoscopy or capsule endoscopy.

“The latter two carry a burden on healthcare costs and hence the testing of stools for either the stool occult blood or the stool DNA analysis for abnormal cells have relevance.”

Regular screenings key to cancer fight

Colorectal cancer is the second most deadly cancer in the US and Europe, but also one of the most preventable. Early detection can lead to survival rates of more than 90 per cent.

Early indicators can be blood in a person's stool, persistent changes to bowel habits and stomach cramps.

Annual testing costs for a patient are minimal, especially when compared with late-stage treatments that can cost an average of $38,469 a year, the American Cancer Society said.

Screening of stool samples is recommended every three years, from the age of 45.

Dr Mahesh Rama Varma, a gastroenterologist at NMC Royal Hospital in Dubai says reliable at-home testing kits could boost screening rates. NMC Hospitals
Dr Mahesh Rama Varma, a gastroenterologist at NMC Royal Hospital in Dubai says reliable at-home testing kits could boost screening rates. NMC Hospitals

Although Dr Varma said existing faecal immunochemical testing (FIT) was generally positive, patients often required a colonoscopy to confirm results.

By comparison, a DNA test that looks for abnormal cell characteristics was 92 per cent accurate in detecting cancer, compared with about 74 per cent for a standard FIT.

“FIT is convenient for a patient to do,” said Dr Varma.

“Dietary and medication restrictions are not needed. It does not require bowel preparation, sedation, or time away from work or family.

“But a stool DNA test such as the ColoAlert in the UAE is a very efficient form of screening, taking into consideration cost effectiveness and better sensitivity.”

Genetic testing of biomarkers in saliva, stools and other body tissues for illness and disease is a rapidly evolving area of medicine.

It can help in the early detection of autoimmune diseases, neurodegenerative or metabolic disease, and some mental health conditions.

Results from clinical trials of ColoAlert have been submitted for approval by the US Food and Drug Administration, but the test has already received regulatory backing in Europe and the UAE.

Mainz Biomed worked with Dante Labs, a company specialising in precision medicine, to develop the testing kits in Italy and the UAE.

Dante Labs has been a popular provider of travel tests for Covid-19 during the pandemic.

Samples will initially be processed at Mainz’s in-house centre and then Dante will purchase Mainz’s PCR assay kits and move all UAE test processing to labs in Dubai.

“Our goal is to bring to the market important diagnostic tools to help treat and prevent cancer indications,” said Guido Baechler, chief executive of Mainz Biomed.

“Our differentiated commercial plan of partnering with third-party laboratories for test kit processing versus the traditional methodology of operating a single facility requires alliances with like-minded companies such as Dante Labs.

"They share our passion for forward-thinking diagnostic test development and marketing strategies.”

ANDROID%20VERSION%20NAMES%2C%20IN%20ORDER
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WITHIN%20SAND
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RESULTS

6.30pm Al Maktoum Challenge Round-1 Group One (PA) US$65,000 (Dirt) 1,600m

Winner RB Money To Burn, Fabrice Veron (jockey), Eric Lemartinel (trainer).

7.05pm Handicap (TB) $175,000 (Turf) 1,200m

Winner Ekhtiyaar, Jim Crowley, Doug Watson.

7.40pm UAE 2000 Guineas Trial Conditions (TB) $100,000 (D) 1,600m

Winner Commanding, Richard Mullen, Satish Seemar.

8.15pm Singspiel Stakes Group Two (TB) $250,000 (T) 1,800m

Winner Benbatl, Christophe Soumillon, Saeed bin Suroor.

8.50pm Handicap (TB) $135,000 (T) 1,600m

Winner Zakouski, William Buick, Charlie Appleby.

9.25pm Al Maktoum Challenge Round-1 Group Two (TB) $350,000 (D) 1,600m

Winner Kimbear, Pat Dobbs, Doug Watson.

10pm Dubai Trophy Conditions (TB) $100,000 (T) 1,200m

Winner Platinum Star, Christophe Soumillon, Saeed bin Suroor.

10.35pm Handicap (TB) $135,000 (T) 1,600m

Winner Key Victory, James Doyle, Charlie Appleby.

Company%20Profile
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UAE squad

Esha Oza (captain), Al Maseera Jahangir, Emily Thomas, Heena Hotchandani, Indhuja Nandakumar, Katie Thompson, Lavanya Keny, Mehak Thakur, Michelle Botha, Rinitha Rajith, Samaira Dharnidharka, Siya Gokhale, Sashikala Silva, Suraksha Kotte, Theertha Satish (wicketkeeper) Udeni Kuruppuarachchige, Vaishnave Mahesh.

UAE tour of Zimbabwe

All matches in Bulawayo
Friday, Sept 26 – First ODI
Sunday, Sept 28 – Second ODI
Tuesday, Sept 30 – Third ODI
Thursday, Oct 2 – Fourth ODI
Sunday, Oct 5 – First T20I
Monday, Oct 6 – Second T20I

AndhaDhun

Director: Sriram Raghavan

Producer: Matchbox Pictures, Viacom18

Cast: Ayushmann Khurrana, Tabu, Radhika Apte, Anil Dhawan

Rating: 3.5/5

The%20specs%3A%20Taycan%20Turbo%20GT
%3Cp%3E%3Cstrong%3EEngine%3A%20%3C%2Fstrong%3EDual%20synchronous%20electric%20motors%0D%3Cbr%3E%3Cstrong%3EPower%3A%20%3C%2Fstrong%3E1%2C108hp%0D%3Cbr%3E%3Cstrong%3ETorque%3A%20%3C%2Fstrong%3E1%2C340Nm%0D%3Cbr%3E%3Cstrong%3ETransmission%3A%20%3C%2Fstrong%3ESingle-speed%20automatic%20(front%20axle)%3B%20two-speed%20transmission%20(rear%20axle)%0D%3Cbr%3E%3Cstrong%3ETouring%20range%3A%20%3C%2Fstrong%3E488-560km%0D%3Cbr%3E%3Cstrong%3EPrice%3A%20%3C%2Fstrong%3EFrom%20Dh928%2C400%0D%3Cbr%3E%3Cstrong%3EOn%20sale%3A%20%3C%2Fstrong%3EOrders%20open%3C%2Fp%3E%0A
Company%20profile
%3Cp%3E%3Cstrong%3ECompany%20name%3A%3C%2Fstrong%3E%20Fasset%0D%3Cbr%3E%3Cstrong%3EStarted%3A%20%3C%2Fstrong%3E2019%0D%3Cbr%3E%3Cstrong%3EFounders%3A%3C%2Fstrong%3E%20Mohammad%20Raafi%20Hossain%2C%20Daniel%20Ahmed%0D%3Cbr%3E%3Cstrong%3EBased%3A%3C%2Fstrong%3E%20Dubai%0D%3Cbr%3E%3Cstrong%3ESector%3A%20%3C%2Fstrong%3EFinTech%0D%3Cbr%3E%3Cstrong%3EInitial%20investment%3A%3C%2Fstrong%3E%20%242.45%20million%0D%3Cbr%3E%3Cstrong%3ECurrent%20number%20of%20staff%3A%3C%2Fstrong%3E%2086%0D%3Cbr%3E%3Cstrong%3EInvestment%20stage%3A%3C%2Fstrong%3E%20Pre-series%20B%0D%3Cbr%3E%3Cstrong%3EInvestors%3A%3C%2Fstrong%3E%20Investcorp%2C%20Liberty%20City%20Ventures%2C%20Fatima%20Gobi%20Ventures%2C%20Primal%20Capital%2C%20Wealthwell%20Ventures%2C%20FHS%20Capital%2C%20VN2%20Capital%2C%20local%20family%20offices%3C%2Fp%3E%0A
Key facilities
  • Olympic-size swimming pool with a split bulkhead for multi-use configurations, including water polo and 50m/25m training lanes
  • Premier League-standard football pitch
  • 400m Olympic running track
  • NBA-spec basketball court with auditorium
  • 600-seat auditorium
  • Spaces for historical and cultural exploration
  • An elevated football field that doubles as a helipad
  • Specialist robotics and science laboratories
  • AR and VR-enabled learning centres
  • Disruption Lab and Research Centre for developing entrepreneurial skills
Israel Palestine on Swedish TV 1958-1989

Director: Goran Hugo Olsson

Rating: 5/5

Real estate tokenisation project

Dubai launched the pilot phase of its real estate tokenisation project last month.

The initiative focuses on converting real estate assets into digital tokens recorded on blockchain technology and helps in streamlining the process of buying, selling and investing, the Dubai Land Department said.

Dubai’s real estate tokenisation market is projected to reach Dh60 billion ($16.33 billion) by 2033, representing 7 per cent of the emirate’s total property transactions, according to the DLD.

Conflict, drought, famine

Estimates of the number of deaths caused by the famine range from 400,000 to 1 million, according to a document prepared for the UK House of Lords in 2024.
It has been claimed that the policies of the Ethiopian government, which took control after deposing Emperor Haile Selassie in a military-led revolution in 1974, contributed to the scale of the famine.
Dr Miriam Bradley, senior lecturer in humanitarian studies at the University of Manchester, has argued that, by the early 1980s, “several government policies combined to cause, rather than prevent, a famine which lasted from 1983 to 1985. Mengistu’s government imposed Stalinist-model agricultural policies involving forced collectivisation and villagisation [relocation of communities into planned villages].
The West became aware of the catastrophe through a series of BBC News reports by journalist Michael Buerk in October 1984 describing a “biblical famine” and containing graphic images of thousands of people, including children, facing starvation.

Band Aid

Bob Geldof, singer with the Irish rock group The Boomtown Rats, formed Band Aid in response to the horrific images shown in the news broadcasts.
With Midge Ure of the band Ultravox, he wrote the hit charity single Do They Know it’s Christmas in December 1984, featuring a string of high-profile musicians.
Following the single’s success, the idea to stage a rock concert evolved.
Live Aid was a series of simultaneous concerts that took place at Wembley Stadium in London, John F Kennedy Stadium in Philadelphia, the US, and at various other venues across the world.
The combined event was broadcast to an estimated worldwide audience of 1.5 billion.

SQUADS

UAE
Mohammed Naveed (captain), Mohamed Usman (vice-captain), Ashfaq Ahmed, Chirag Suri, Shaiman Anwar, Mohammed Boota, Ghulam Shabber, Imran Haider, Tahir Mughal, Amir Hayat, Zahoor Khan, Qadeer Ahmed, Fahad Nawaz, Abdul Shakoor, Sultan Ahmed, CP Rizwan

Nepal
Paras Khadka (captain), Gyanendra Malla, Dipendra Singh Airee, Pradeep Airee, Binod Bhandari, Avinash Bohara, Sundeep Jora, Sompal Kami, Karan KC, Rohit Paudel, Sandeep Lamichhane, Lalit Rajbanshi, Basant Regmi, Pawan Sarraf, Bhim Sharki, Aarif Sheikh

Lexus LX700h specs

Engine: 3.4-litre twin-turbo V6 plus supplementary electric motor

Power: 464hp at 5,200rpm

Torque: 790Nm from 2,000-3,600rpm

Transmission: 10-speed auto

Fuel consumption: 11.7L/100km

On sale: Now

Price: From Dh590,000

THE BIO

Born: Mukalla, Yemen, 1979

Education: UAE University, Al Ain

Family: Married with two daughters: Asayel, 7, and Sara, 6

Favourite piece of music: Horse Dance by Naseer Shamma

Favourite book: Science and geology

Favourite place to travel to: Washington DC

Best advice you’ve ever been given: If you have a dream, you have to believe it, then you will see it.

The Prison Letters of Nelson Mandela
Edited by Sahm Venter
Published by Liveright

BLACK%20ADAM
%3Cp%3E%3Cstrong%3EDirector%3A%3C%2Fstrong%3E%20Jaume%20Collet-Serra%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EStars%3A%3C%2Fstrong%3E%20Dwayne%20Johnson%2C%20Sarah%20Shahi%2C%20Viola%20Davis%2C%20Pierce%20Brosnan%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3ERating%3A%20%3C%2Fstrong%3E3%2F5%3C%2Fp%3E%0A

Various Artists 
Habibi Funk: An Eclectic Selection Of Music From The Arab World (Habibi Funk)
​​​​​​​

What is graphene?

Graphene is extracted from graphite and is made up of pure carbon.

It is 200 times more resistant than steel and five times lighter than aluminum.

It conducts electricity better than any other material at room temperature.

It is thought that graphene could boost the useful life of batteries by 10 per cent.

Graphene can also detect cancer cells in the early stages of the disease.

The material was first discovered when Andre Geim and Konstantin Novoselov were 'playing' with graphite at the University of Manchester in 2004.

Our legal consultant

Name: Dr Hassan Mohsen Elhais

Position: legal consultant with Al Rowaad Advocates and Legal Consultants.

Results
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Barbie
%3Cp%3E%3Cstrong%3EDirector%3A%3C%2Fstrong%3E%20Greta%20Gerwig%3Cbr%3E%3Cstrong%3EStars%3A%3C%2Fstrong%3E%20Margot%20Robbie%2C%20Ryan%20Gosling%2C%20Will%20Ferrell%2C%20America%20Ferrera%3Cbr%3E%3Cstrong%3ERating%3A%3C%2Fstrong%3E%204%2F5%3Cbr%3E%3C%2Fp%3E%0A
Living in...

This article is part of a guide on where to live in the UAE. Our reporters will profile some of the country’s most desirable districts, provide an estimate of rental prices and introduce you to some of the residents who call each area home.

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The%20specs%3A%202024%20Panamera
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The%20specs
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Benefits of first-time home buyers' scheme
  • Priority access to new homes from participating developers
  • Discounts on sales price of off-plan units
  • Flexible payment plans from developers
  • Mortgages with better interest rates, faster approval times and reduced fees
  • DLD registration fee can be paid through banks or credit cards at zero interest rates
Plan to boost public schools

A major shake-up of government-run schools was rolled out across the country in 2017. Known as the Emirati School Model, it placed more emphasis on maths and science while also adding practical skills to the curriculum.

It was accompanied by the promise of a Dh5 billion investment, over six years, to pay for state-of-the-art infrastructure improvements.

Aspects of the school model will be extended to international private schools, the education minister has previously suggested.

Recent developments have also included the introduction of moral education - which public and private schools both must teach - along with reform of the exams system and tougher teacher licensing requirements.

Listen to Extra Time
Updated: May 19, 2022, 7:15 AM`