Vinicius Junior scored twice as Real Madrid made Liverpool pay for defensive errors with a 3-1 victory putting them in sight of the Champions League semi-finals.
Vinicius and Marco Asensio both profited in the first half after darting behind Liverpool's makeshift back-line before a simple move from a throw-in gave Vinicius a simple finish in the second period.
Mohamed Salah's strike shortly after the interval briefly made it a contest at Valdebebas, with an away goal certainly a significant consolation for Liverpool to take into the second leg at Anfield next week.
But without fans and with a miserable recent record at home, manager Jurgen Klopp will know his side have it all to do to avoid his team's season becoming solely about scraping into the Premier League's top four.
"We didn't play well enough, that's my first concern," said Klopp. "We didn't deserve to win tonight, but the good news is that there is another match.
"We are going to fight, 3-1 is not good, but we have a chance."
Player ratings from the match can be seen in the picture gallery above. To view the next image, click on the arrows or swipe if on a mobile device.
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THE SPECS
Engine: 6.75-litre twin-turbocharged V12 petrol engine
Power: 420kW
Torque: 780Nm
Transmission: 8-speed automatic
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ENGLAND SQUAD
Goalkeepers: Jack Butland, Jordan Pickford, Nick Pope
Defenders: John Stones, Harry Maguire, Phil Jones, Kyle Walker, Kieran Trippier, Gary Cahill, Ashley Young, Danny Rose, Trent Alexander-Arnold
Midfielders: Eric Dier, Jordan Henderson, Dele Alli, Jesse Lingard, Raheem Sterling, Ruben Loftus-Cheek, Fabian Delph
Forwards: Harry Kane, Jamie Vardy, Marcus Rashford, Danny Welbeck
23-man shortlist for next six Hall of Fame inductees
Tony Adams, David Beckham, Dennis Bergkamp, Sol Campbell, Eric Cantona, Andrew Cole, Ashley Cole, Didier Drogba, Les Ferdinand, Rio Ferdinand, Robbie Fowler, Steven Gerrard, Roy Keane, Frank Lampard, Matt Le Tissier, Michael Owen, Peter Schmeichel, Paul Scholes, John Terry, Robin van Persie, Nemanja Vidic, Patrick Viera, Ian Wright.
Meatless Days
Sara Suleri, with an introduction by Kamila Shamsie
Penguin
Results
United States beat UAE by three wickets
United States beat Scotland by 35 runs
UAE v Scotland – no result
United States beat UAE by 98 runs
Scotland beat United States by four wickets
Fixtures
Sunday, 10am, ICC Academy, Dubai - UAE v Scotland
Admission is free