Manchester United v Liverpool (7.30pm): Liverpool are looking in great touch, banging in goals for fun and have the world's most in-form striker in Mohamed Salah. United are going through a rough patch in the league but will have been boosted by their comeback win against Atalanta midweek. Prediction: United 1 Liverpool 3. Reuters
FRIDAY, OCTOBER 22 - Arsenal v Aston Villa (11pm): Consistency is a problem for both of teams. Arsenal followed up their three-game win streak with two frustrating draws while Villa have lost their last two matches, having won the previous couple, and are set to make it an unwanted hat-trick here. Prediction: Arsenal 2 Villa 1. PA
SATURDAY - Chelsea v Norwich (3.30pm): Losing key forwards Romelu Lukaku and Timo Werner to injury midweek will be a blow for Chelsea but it there's any team you would want to be playing now, it would be bottom dwellers Norwich. The Canaries are eight games into the season but have just two points and two goals. Prediction: Chelsea 3 Norwich 1. PA
Crystal Palace v Newcastle (6pm): Palace made it five draws out of eight games last week against Arsenal - but deserved all three points. For Newcastle, Steve Bruce was finally put out of his misery this week, leaving his assistant, Graeme Jones, in temporary charge with the Magpies still looking for their first win. Prediction: Palace 1 Newcastle 2. Reuters
Everton v Watford (6pm): Watford manager Claudio Ranieri was given a tough welcome back to the Premier League when his new team were thrashed 5-0 by Liverpool. Everton suffered a home defeat - 1-0 to West Ham - and could do with more points on the board with a tough run of games coming up. Prediction: Everton 2 Watford 0. PA
Leeds v Wolves (6pm): Wolves suddenly find themselves on a roll after a torrid start to the season and now have three wins on the spin. Their latest saw them come back from 2-0 down to beat Aston Villa. Leeds continue to look a shadow of last season's exciting outfit and sit just outside the bottom three. Prediction: Leeds 1 Wolves 1. Reuters
Southampton v Burnley (6pm): The Saints secured their first win of the campaign against Leeds last week, at the eighth attempt. Burnley, though, still await their first victory and sit third bottom on three points. No joy here again for the Clarets. Prediction: Southampton 1 Burnley 0. AFP
Brighton v Manchester City (8.30pm): A top-four clash that few would have predicted at the start of the campaign. The Seagulls are fourth in the table, having lost just once, but come up against a City side who seem to have hit that winning combo of scoring goals and not conceding many. Prediction: Brighton 1 City 3. Reuters
SUNDAY - Brentford v Leicester City (5pm): The Foxes will be flying after their 4-2 destruction of Manchester United, followed up by their comeback win at Spartak Moscow in the Europe League. Brentford, though, continue to surprise and deserved at least a point from their narrow defeat to Chelsea. Prediction: Brentford 2 Leicester 2. Reuters
West Ham v Tottenham (6pm): A tough London derby to call here. Both teams are knocking on the door of the top four and both earned hard-fought victories last week - against Everton and Newcastle, respectively. Honours even at the London Stadium. Prediction: West Ham 1 Spurs 1. Reuters
Manchester United v Liverpool (7.30pm): Liverpool are looking in great touch, banging in goals for fun and have the world's most in-form striker in Mohamed Salah. United are going through a rough patch in the league but will have been boosted by their comeback win against Atalanta midweek. Prediction: United 1 Liverpool 3. Reuters
FRIDAY, OCTOBER 22 - Arsenal v Aston Villa (11pm): Consistency is a problem for both of teams. Arsenal followed up their three-game win streak with two frustrating draws while Villa have lost their last two matches, having won the previous couple, and are set to make it an unwanted hat-trick here. Prediction: Arsenal 2 Villa 1. PA
SATURDAY - Chelsea v Norwich (3.30pm): Losing key forwards Romelu Lukaku and Timo Werner to injury midweek will be a blow for Chelsea but it there's any team you would want to be playing now, it would be bottom dwellers Norwich. The Canaries are eight games into the season but have just two points and two goals. Prediction: Chelsea 3 Norwich 1. PA
Crystal Palace v Newcastle (6pm): Palace made it five draws out of eight games last week against Arsenal - but deserved all three points. For Newcastle, Steve Bruce was finally put out of his misery this week, leaving his assistant, Graeme Jones, in temporary charge with the Magpies still looking for their first win. Prediction: Palace 1 Newcastle 2. Reuters
Everton v Watford (6pm): Watford manager Claudio Ranieri was given a tough welcome back to the Premier League when his new team were thrashed 5-0 by Liverpool. Everton suffered a home defeat - 1-0 to West Ham - and could do with more points on the board with a tough run of games coming up. Prediction: Everton 2 Watford 0. PA
Leeds v Wolves (6pm): Wolves suddenly find themselves on a roll after a torrid start to the season and now have three wins on the spin. Their latest saw them come back from 2-0 down to beat Aston Villa. Leeds continue to look a shadow of last season's exciting outfit and sit just outside the bottom three. Prediction: Leeds 1 Wolves 1. Reuters
Southampton v Burnley (6pm): The Saints secured their first win of the campaign against Leeds last week, at the eighth attempt. Burnley, though, still await their first victory and sit third bottom on three points. No joy here again for the Clarets. Prediction: Southampton 1 Burnley 0. AFP
Brighton v Manchester City (8.30pm): A top-four clash that few would have predicted at the start of the campaign. The Seagulls are fourth in the table, having lost just once, but come up against a City side who seem to have hit that winning combo of scoring goals and not conceding many. Prediction: Brighton 1 City 3. Reuters
SUNDAY - Brentford v Leicester City (5pm): The Foxes will be flying after their 4-2 destruction of Manchester United, followed up by their comeback win at Spartak Moscow in the Europe League. Brentford, though, continue to surprise and deserved at least a point from their narrow defeat to Chelsea. Prediction: Brentford 2 Leicester 2. Reuters
West Ham v Tottenham (6pm): A tough London derby to call here. Both teams are knocking on the door of the top four and both earned hard-fought victories last week - against Everton and Newcastle, respectively. Honours even at the London Stadium. Prediction: West Ham 1 Spurs 1. Reuters
Manchester United v Liverpool (7.30pm): Liverpool are looking in great touch, banging in goals for fun and have the world's most in-form striker in Mohamed Salah. United are going through a rough patch in the league but will have been boosted by their comeback win against Atalanta midweek. Prediction: United 1 Liverpool 3. Reuters