The wild poliovirus is “cornered” in the last two countries where it is found, a leading expert has said as efforts continue to eradicate the pathogen.
In a briefing to mark a decade since India was declared polio-free, clinicians have said that progress is being made to eliminate the virus in the last two nations where it is endemic – Pakistan and Afghanistan.
With flare-ups remaining a threat even in high-income nations, clinicians say there is no room for complacency in the battle against the sometimes-fatal disease.
The UAE has been one of the leading players in the fight against polio, having financed vaccination efforts and supported initiatives to mobilise international action.
Polio vaccination drive in Pakistan – in pictures
Poliomyelitis primarily affects young children who, in severe cases, may become paralysed or even die after contracting the virus.
“We have Pakistan and Afghanistan [where polio is] still endemic, but the virus is cornered in very few pockets in very few districts,” Dr Ananda Bandyopadhyay, deputy director of polio technology, research and analytics at the Bill & Melinda Gates Foundation, said.
Dr Bandyopadhyay said there had been more than 10 genetic families of the virus in these two countries, but this has now fallen to two.
“It indicates the virus is cornered,” he added.
Continued efforts to vaccinate populations have been credited with helping to eliminate pockets of the disease in Afghanistan and Pakistan.
However, there can be hazards for people engaged in the vaccine roll-out in these two nations. Anti-vaccine sentiment has even resulted in the murder of medical staff engaged in immunisation efforts and of police protecting them. The wild poliovirus can also continue to circulate in some areas where populations are hard to reach.
An injectable inactivated polio vaccine was introduced in 1955, with the oral polio vaccine, taken as drops in the mouth, following six years later.
Investing in global polio fight
In 1988, more than three decades after vaccination efforts began, there were still, World Health Organisation figures indicate, 350,000 cases caused by wild poliovirus, which remained endemic in 125 nations.
That year saw the launch of the Global Polio Eradication Initiative led by the WHO, the UN children’s fund Unicef, Rotary International, the US Centres for Disease Control and Prevention (CDC) and the Bill & Melinda Gates Foundation.
Continued efforts resulted in India and the WHO’s South-East Asia region being declared polio-free in March 2014.
Some thought that, in a country as large as India, where many live in absolute poverty, it would be impossible to eliminate polio.
“People used to tell us it was a pipe dream,” Dr Hamid Jafari, director of polio eradication for the WHO’s Regional Office for the Eastern Mediterranean, said.
“The eradication of polio in India proves beyond doubt the biological and technical feasibility of polio eradication.”
He said that lessons learnt in India have been applied to the other remaining countries where the wild poliovirus circulates.
Another major milestone was reached in June 2020, when Nigeria, one of just three countries where wild poliovirus still circulated, was declared polio-free.
The oral polio vaccine contains a weakened form of the polio virus that in rare cases mutates, becomes pathogenic and circulates in poorly immunised populations, causing circulating vaccine-derived poliovirus (cVDPV). In a very small proportion of cases this, like the wild poliovirus, can cause paralysis.
In recent years there have been cases of cVDPV even in high-income nations including Israel, Britain and the US.
The UK and the US administer an inactivated polio vaccine and do not use the oral polio vaccine, so cases of cVDPV in these nations are thought to have emerged from the virus being brought in.
In March 2021 the novel oral polio vaccine type 2 (nOPV2) was introduced on an emergency basis, representing a step forward because it is genetically stable, reducing the risk of cVDPV. About a billion doses of nOPV2 have now been administered in 35 countries.
The UAE has been one of the leaders in the fight against polio, with the UAE Pakistan Vaccination Assistance Programme having delivered over half a billion vaccine doses in the South Asian country over the past decade.
Since 2014 President Sheikh Mohamed has contributed hundreds of millions of dollars to vaccination and polio eradication campaigns.
In 2013 Abu Dhabi hosted, in partnership with Ban Ki-moon, then the UN secretary-general, and Bill Gates, the co-chair of the Bill & Melinda Gates Foundation, a groundbreaking Global Vaccine Summit where $4 billion was pledged to support the fight against polio.
Dr Jay Wenger, director of polio at the Bill & Melinda Gates Foundation, said that efforts had to continue to try to eradicate the disease.
“We have to push to the end or we won’t quite make it,” he said.
Key facilities
- Olympic-size swimming pool with a split bulkhead for multi-use configurations, including water polo and 50m/25m training lanes
- Premier League-standard football pitch
- 400m Olympic running track
- NBA-spec basketball court with auditorium
- 600-seat auditorium
- Spaces for historical and cultural exploration
- An elevated football field that doubles as a helipad
- Specialist robotics and science laboratories
- AR and VR-enabled learning centres
- Disruption Lab and Research Centre for developing entrepreneurial skills
UAE currency: the story behind the money in your pockets
Killing of Qassem Suleimani
Dengue%20fever%20symptoms
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UAE currency: the story behind the money in your pockets
Key recommendations
- Fewer criminals put behind bars and more to serve sentences in the community, with short sentences scrapped and many inmates released earlier.
- Greater use of curfews and exclusion zones to deliver tougher supervision than ever on criminals.
- Explore wider powers for judges to punish offenders by blocking them from attending football matches, banning them from driving or travelling abroad through an expansion of ‘ancillary orders’.
- More Intensive Supervision Courts to tackle the root causes of crime such as alcohol and drug abuse – forcing repeat offenders to take part in tough treatment programmes or face prison.
The five pillars of Islam
Employment lawyer Meriel Schindler of Withers Worldwide shares her tips on achieving equal pay
Do your homework
Make sure that you are being offered a fair salary. There is lots of industry data available, and you can always talk to people who have come out of the organisation. Where I see people coming a cropper is where they haven’t done their homework.
Don’t be afraid to negotiate
It’s quite standard to negotiate if you think an offer is on the low side. The job is unlikely to be withdrawn if you ask for money, and if that did happen I’d question whether you want to work for an employer who is so hypersensitive.
Know your worth
Women tend to be a bit more reticent to talk about their achievements. In my experience they need to have more confidence in their own abilities – men will big up what they’ve done to get a pay rise, and to compete women need to turn up the volume.
Work together
If you suspect men in your organisation are being paid more, look your boss in the eye and say, “I want you to assure me that I’m paid equivalent to my peers”. If you’re not getting a straight answer, talk to your peer group and consider taking direct action to fix inequality.
Results
4.30pm Jebel Jais – Maiden (PA) Dh60,000 (Turf) 1,000m; Winner: MM Al Balqaa, Bernardo Pinheiro (jockey), Qaiss Aboud (trainer)
5pm: Jabel Faya – Maiden (PA) Dh60,000 (T) 1,000m; Winner: AF Rasam, Tadhg O’Shea, Ernst Oertel
5.30pm: Al Wathba Stallions Cup – Handicap (PA) Dh70,000 (T) 2,200m; Winner: AF Mukhrej, Tadhg O’Shea, Ernst Oertel
6pm: The President’s Cup Prep – Conditions (PA) Dh100,000 (T) 2,200m; Winner: Mujeeb, Richard Mullen, Salem Al Ketbi
6.30pm: Abu Dhabi Equestrian Club – Prestige (PA) Dh125,000 (T) 1,600m; Winner: Jawal Al Reef, Antonio Fresu, Abubakar Daud
7pm: Al Ruwais – Group 3 (PA) Dh300,000 (T) 1,200m; Winner: Ashton Tourettes, Pat Dobbs, Ibrahim Aseel
7.30pm: Jebel Hafeet – Maiden (TB) Dh80,000 (T) 1,400m; Winner: Nibraas, Richard Mullen, Nicholas Bachalard
The Facility’s Versatility
Between the start of the 2020 IPL on September 20, and the end of the Pakistan Super League this coming Thursday, the Zayed Cricket Stadium has had an unprecedented amount of traffic.
Never before has a ground in this country – or perhaps anywhere in the world – had such a volume of major-match cricket.
And yet scoring has remained high, and Abu Dhabi has seen some classic encounters in every format of the game.
October 18, IPL, Kolkata Knight Riders tied with Sunrisers Hyderabad
The two playoff-chasing sides put on 163 apiece, before Kolkata went on to win the Super Over
January 8, ODI, UAE beat Ireland by six wickets
A century by CP Rizwan underpinned one of UAE’s greatest ever wins, as they chased 270 to win with an over to spare
February 6, T10, Northern Warriors beat Delhi Bulls by eight wickets
The final of the T10 was chiefly memorable for a ferocious over of fast bowling from Fidel Edwards to Nicholas Pooran
March 14, Test, Afghanistan beat Zimbabwe by six wickets
Eleven wickets for Rashid Khan, 1,305 runs scored in five days, and a last session finish
June 17, PSL, Islamabad United beat Peshawar Zalmi by 15 runs
Usman Khawaja scored a hundred as Islamabad posted the highest score ever by a Pakistan team in T20 cricket
UAE Premiership
Results
Dubai Exiles 24-28 Jebel Ali Dragons
Abu Dhabi Harlequins 43-27 Dubai Hurricanes
Final
Abu Dhabi Harlequins v Jebel Ali Dragons, Friday, March 29, 5pm at The Sevens, Dubai
The specs: 2017 Ford F-150 Raptor
Price, base / as tested Dh220,000 / Dh320,000
Engine 3.5L V6
Transmission 10-speed automatic
Power 421hp @ 6,000rpm
Torque 678Nm @ 3,750rpm
Fuel economy, combined 14.1L / 100km
Try out the test yourself
Q1 Suppose you had $100 in a savings account and the interest rate was 2 per cent per year. After five years, how much do you think you would have in the account if you left the money to grow?
a) More than $102
b) Exactly $102
c) Less than $102
d) Do not know
e) Refuse to answer
Q2 Imagine that the interest rate on your savings account was 1 per cent per year and inflation was 2 per cent per year. After one year, how much would you be able to buy with the money in this account?
a) More than today
b) Exactly the same as today
c) Less than today
d) Do not know
e) Refuse to answer
Q4 Do you think that the following statement is true or false? “Buying a single company stock usually provides a safer return than a stock mutual fund.”
a) True
b) False
d) Do not know
e) Refuse to answer
The “Big Three” financial literacy questions were created by Professors Annamaria Lusardi of the George Washington School of Business and Olivia Mitchell, of the Wharton School of the University of Pennsylvania.
Answers: Q1 More than $102 (compound interest). Q2 Less than today (inflation). Q3 False (diversification).
Jetour T1 specs
Engine: 2-litre turbocharged
Power: 254hp
Torque: 390Nm
Price: From Dh126,000
Available: Now
Specs
Engine: Dual-motor all-wheel-drive electric
Range: Up to 610km
Power: 905hp
Torque: 985Nm
Price: From Dh439,000
Available: Now
Company%20profile
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COMPANY%20PROFILE
%3Cp%3E%3Cstrong%3EName%3A%20%3C%2Fstrong%3EEjari%3Cbr%3E%3Cstrong%3EBased%3A%20%3C%2Fstrong%3ERiyadh%2C%20Saudi%20Arabia%3Cbr%3E%3Cstrong%3EFounders%3A%20%3C%2Fstrong%3EYazeed%20Al%20Shamsi%2C%20Fahad%20Albedah%2C%20Mohammed%20Alkhelewy%20and%20Khalid%20Almunif%3Cbr%3E%3Cstrong%3ESector%3A%20%3C%2Fstrong%3EPropTech%3Cbr%3E%3Cstrong%3ETotal%20funding%3A%20%3C%2Fstrong%3E%241%20million%3Cbr%3E%3Cstrong%3EInvestors%3A%20%3C%2Fstrong%3ESanabil%20500%20Mena%2C%20Hambro%20Perks'%20Oryx%20Fund%20and%20angel%20investors%3Cbr%3E%3Cstrong%3ENumber%20of%20employees%3A%20%3C%2Fstrong%3E8%3C%2Fp%3E%0A
Red flags
- Promises of high, fixed or 'guaranteed' returns.
- Unregulated structured products or complex investments often used to bypass traditional safeguards.
- Lack of clear information, vague language, no access to audited financials.
- Overseas companies targeting investors in other jurisdictions - this can make legal recovery difficult.
- Hard-selling tactics - creating urgency, offering 'exclusive' deals.
Courtesy: Carol Glynn, founder of Conscious Finance Coaching
BIGGEST CYBER SECURITY INCIDENTS IN RECENT TIMES
SolarWinds supply chain attack: Came to light in December 2020 but had taken root for several months, compromising major tech companies, governments and its entities
Microsoft Exchange server exploitation: March 2021; attackers used a vulnerability to steal emails
Kaseya attack: July 2021; ransomware hit perpetrated REvil, resulting in severe downtime for more than 1,000 companies
Log4j breach: December 2021; attackers exploited the Java-written code to inflitrate businesses and governments
PREMIER LEAGUE FIXTURES
All times UAE ( 4 GMT)
Saturday
West Ham United v Tottenham Hotspur (3.30pm)
Burnley v Huddersfield Town (7pm)
Everton v Bournemouth (7pm)
Manchester City v Crystal Palace (7pm)
Southampton v Manchester United (7pm)
Stoke City v Chelsea (7pm)
Swansea City v Watford (7pm)
Leicester City v Liverpool (8.30pm)
Sunday
Brighton and Hove Albion v Newcastle United (7pm)
Monday
Arsenal v West Bromwich Albion (11pm)
Cryopreservation: A timeline
- Keyhole surgery under general anaesthetic
- Ovarian tissue surgically removed
- Tissue processed in a high-tech facility
- Tissue re-implanted at a time of the patient’s choosing
- Full hormone production regained within 4-6 months
The specs
Engine: 3.5-litre V6
Power: 272hp at 6,400rpm
Torque: 331Nm from 5,000rpm
Transmission: 8-speed auto
Fuel consumption: 9.7L/100km
On sale: now
Price: Dh149,000
CONFIRMED%20LINE-UP
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AS%20WE%20EXIST
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UAE currency: the story behind the money in your pockets