Scientists have discovered a way to see inside the body by making skin appear invisible, paving the way for medics to be able to detect skin cancer earlier and make drawing blood easier.
By using common food dye, researchers found they could penetrate skin and view its inner workings, making conditions like cancer and digestive issues easier to spot.
The revolutionary technique renders the body’s overlying tissues transparent to visible light enabling the organs inside to be seen.
Stanford University researchers used food-safe dyes, which were reversible in tests, on mice. It has not yet been tested on humans.
The US National Science Foundation described the development as creating "a window into the body" through a technique "which makes skin invisible".
In research published on Thursday in publication Science, called Achieving optical transparency in live animals with absorbing molecule, the scientists hope it could ultimately be applied to a wide range of medical diagnostics, from locating injuries to monitoring digestive disorders to identifying cancers.
Guosong Hong, assistant professor of materials science and engineering at Stanford, and senior author on the paper, told The National it will improve several procedures.
"Looking forward, this technology could make veins more visible, easing the process of venepuncture - the procedure of drawing blood or administering fluids via a needle - especially for elderly patients with veins that are difficult to locate," he said.
"Moreover, this innovation could assist in the early detection of skin cancer, improve light penetration for deep tissue treatments like photodynamic and photothermal therapies, and make laser-based tattoo removal more straightforward."
To master the new technique, the researchers developed a way to predict how light interacts with dyed biological tissues.
Using refraction, the process by which light changes speed and bends as it travels from one material into another, and knowledge of the way light scatters, the researchers examined how they could find a way to enable light to travel through the body unimpeded.
Due to fats, fluids within cells and proteins having different refractive properties effecting how significantly a light wave will bend, it has not been possible to transparently see the body’s organs.
So they set about finding a way to match the different refractive indices so light could travel through unimpeded.
They realised that dyes that are effective at absorbing light could also be highly effective at directing light uniformly through a wide range of refractive indices.
The team dissolved yellow food dye tartrazine, also known as FD & C Yellow 5, into water, then let tissues absorb it and discovered it prevented light from scattering and resulted in transparency.
The researchers first successfully tested their theory on thin slices of chicken breast and then used the solution on the scalps of mice, which rendered the skin transparent to reveal blood vessels criss-crossing the brain.
Using the same techniques on mice's abdomens, it allowed them to see the contractions of the intestine and movements caused by heartbeats and breathing.
The researchers suspect that injecting the dye should lead to even deeper views within organisms, with implications for both biology and medicine.
They began to research how microwave radiation interacts with biological tissues and by exploring historic optics textbooks, they found a mathematical equation called Kramers-Kronig and a phenomenon called Lorentz oscillation, where electrons and atoms resonate within molecules as photons pass through, and looked at how they could be applied to medicine.
They found these tools proved ideal for predicting how a given dye can raise the refractive index of biological fluids to perfectly match surrounding fats and proteins.
Using an ellipsometry, which is an optical technique used in industry to measure the thickness of a thin film, they applied the science to biology in a medical first to predict the optical properties of their target dyes.
″While a basic workhorse such as an ellipsometer would rarely make headlines, it nevertheless can play a crucial role when deployed for atypical uses like the case here," said NSF Program Officer Richard Nash, who oversees the NSF NNCI.
"Open access to such instrumentation is foundational for making groundbreaking discoveries, as those instruments can be deployed in new ways to generate fundamental insights about scientific phenomena.″
The researchers hope their approach will launch a new field of study matching dyes to biological tissues based on optical properties, potentially leading to a wide range of medical applications.
″As an optics person, I’m amazed at how they got so much from exploiting the Kramers-Konig relationship,″ said NSF Program Officer Adam Wax.
″Every optics student learns about them, but this team has used the equations to figure out how a strongly absorbing dye can make skin transparent. Using an NSF EAGER grant, Mr Hong was able to step out in a bold new direction, a great example of how fundamental optics knowledge can be used to create new technologies, including in biomedicine.″
Killing of Qassem Suleimani
Profile box
Founders: Michele Ferrario, Nino Ulsamer and Freddy Lim
Started: established in 2016 and launched in July 2017
Based: Singapore, with offices in the UAE, Malaysia, Hong Kong, Thailand
Sector: FinTech, wealth management
Initial investment: $500,000 in seed round 1 in 2016; $2.2m in seed round 2 in 2017; $5m in series A round in 2018; $12m in series B round in 2019; $16m in series C round in 2020 and $25m in series D round in 2021
Current staff: more than 160 employees
Stage: series D
Investors: EightRoads Ventures, Square Peg Capital, Sequoia Capital India
F1 The Movie
Starring: Brad Pitt, Damson Idris, Kerry Condon, Javier Bardem
Director: Joseph Kosinski
Rating: 4/5
BIGGEST CYBER SECURITY INCIDENTS IN RECENT TIMES
SolarWinds supply chain attack: Came to light in December 2020 but had taken root for several months, compromising major tech companies, governments and its entities
Microsoft Exchange server exploitation: March 2021; attackers used a vulnerability to steal emails
Kaseya attack: July 2021; ransomware hit perpetrated REvil, resulting in severe downtime for more than 1,000 companies
Log4j breach: December 2021; attackers exploited the Java-written code to inflitrate businesses and governments
ESSENTIALS
The flights
Emirates flies from Dubai to Phnom Penh via Yangon from Dh2,700 return including taxes. Cambodia Bayon Airlines and Cambodia Angkor Air offer return flights from Phnom Penh to Siem Reap from Dh250 return including taxes. The flight takes about 45 minutes.
The hotels
Rooms at the Raffles Le Royal in Phnom Penh cost from $225 (Dh826) per night including taxes. Rooms at the Grand Hotel d'Angkor cost from $261 (Dh960) per night including taxes.
The tours
A cyclo architecture tour of Phnom Penh costs from $20 (Dh75) per person for about three hours, with Khmer Architecture Tours. Tailor-made tours of all of Cambodia, or sites like Angkor alone, can be arranged by About Asia Travel. Emirates Holidays also offers packages.
Specs
Engine: Electric motor generating 54.2kWh (Cooper SE and Aceman SE), 64.6kW (Countryman All4 SE)
Power: 218hp (Cooper and Aceman), 313hp (Countryman)
Torque: 330Nm (Cooper and Aceman), 494Nm (Countryman)
On sale: Now
Price: From Dh158,000 (Cooper), Dh168,000 (Aceman), Dh190,000 (Countryman)
More from Rashmee Roshan Lall
The specs: 2017 Dodge Viper SRT
Price, base / as tested Dh460,000
Engine 8.4L V10
Transmission Six-speed manual
Power 645hp @ 6,200rpm
Torque 813Nm @ 5,000rpm
Fuel economy, combined 16.8L / 100km
Killing of Qassem Suleimani
The specs
Engine: 3.0-litre six-cylinder turbo
Power: 398hp from 5,250rpm
Torque: 580Nm at 1,900-4,800rpm
Transmission: Eight-speed auto
Fuel economy, combined: 6.5L/100km
On sale: December
Price: From Dh330,000 (estimate)
Results
Male 51kg Round 1
Dias Karmanov (KAZ) beat Mabrook Rasea (YEM) by points 2-1.
Male 54kg Round 1
Yelaman Sayassatov (KAZ) beat Chen Huang (TPE) TKO Round 1; Huynh Hoang Phi (VIE) beat Fahad Anakkayi (IND) RSC Round 2; Qais Al Jamal (JOR) beat Man Long Ng (MAC) by points 3-0; Ayad Albadr (IRQ) beat Yashar Yazdani (IRI) by points 2-1.
Male 57kg Round 1
Natthawat Suzikong (THA) beat Abdallah Ondash (LBN) by points 3-0; Almaz Sarsembekov (KAZ) beat Ahmed Al Jubainawi (IRQ) by points 2-1; Hamed Almatari (YEM) beat Nasser Al Rugheeb (KUW) by points 3-0; Zakaria El Jamari (UAE) beat Yu Xi Chen (TPE) by points 3-0.
Men 86kg Round 1
Ahmad Bahman (UAE) beat Mohammad Al Khatib (PAL) by points 2-1
Men 63.5kg Round 1
Noureddin Samir (UAE) beat Polash Chakma (BAN) RSC Round 1.
Female 45kg quarter finals
Narges Mohammadpour (IRI) beat Yuen Wai Chan (HKG) by points.
Female 48kg quarter finals
Szi Ki Wong (HKG) beat Dimple Vaishnav (IND) RSC round 2; Thanawan Thongduang (THA) beat Nastaran Soori (IRI) by points; Shabnam Hussain Zada (AFG) beat Tzu Ching Lin (TPE) by points.
Female 57kg quarter finals
Nguyen Thi Nguyet (VIE) beat Anisha Shetty (IND) by points 2-1; Areeya Sahot (THA) beat Dana Al Mayyal (KUW) RSC Round 1; Sara Idriss (LBN) beat Ching Yee Tsang (HKG) by points 3-0.
RESULTS
%3Cp%3E%0D5pm%3A%20Deerfields%20%E2%80%93%20Handicap%20(PA)%20Dh80%2C000%20(Turf)%202%2C200m%0D%3Cbr%3EWinner%3A%20Taajer%2C%20Richard%20Mullen%20(jockey)%2C%20Salem%20Al%20Ketbi%20(trainer)%0D%3Cbr%3E5.30pm%3A%20The%20Galleria%20%E2%80%93%20Handicap%20(PA)%20Dh80%2C000%20(T)%201%2C600m%0D%3Cbr%3EWinner%3A%20Zafaranah%2C%20Antonio%20Fresu%2C%20Musabah%20Al%20Muhairi%0D%3Cbr%3E6pm%3A%20Wathba%20Stallions%20Cup%20%E2%80%93%20Maiden%20(PA)%20Dh70%2C000%20(T)%201%2C200m%0D%3Cbr%3EWinner%3A%20Ifahat%20Du%20Loup%2C%20Abdul%20Aziz%20Al%20Balushi%2C%20Sulaiman%20Al%20Ghunaimi%0D%3Cbr%3E6.30pm%3A%20Mazyad%20%E2%80%93%20Handicap%20(PA)%20Dh80%2C000%20(T)%201%2C200m%0D%3Cbr%3EWinner%3A%20AF%20Majalis%2C%20Tadhg%20O%E2%80%99Shea%2C%20Ernst%20Oertel%0D%3Cbr%3E7pm%3A%20Dalma%20%E2%80%93%20Maiden%20(PA)%20Dh80%2C000%20(T)%201%2C400m%0D%3Cbr%3EWinner%3A%20Bassam%20Al%20Wathba%2C%20Bernardi%20Pinheiro%2C%20Majed%20Al%20Jahouri%0D%3Cbr%3E7.30pm%3A%20World%20Trade%20Centre%20%E2%80%93%20Handicap%20(TB)%20Dh80%2C000%20(T)%201%2C400m%0D%3Cbr%3EWinner%3A%20Fawaareq%2C%20Dane%20O%E2%80%99Neill%2C%20Doug%20Watson%3C%2Fp%3E%0A
Motori Profile
Date started: March 2020
Co-founder/CEO: Ahmed Eissa
Based: UAE, Abu Dhabi
Sector: Insurance Sector
Size: 50 full-time employees (Inside and Outside UAE)
Stage: Seed stage and seeking Series A round of financing
Investors: Safe City Group
COMPANY%20PROFILE
%3Cp%3E%3Cstrong%3EName%3A%20%3C%2Fstrong%3ESmartCrowd%0D%3Cbr%3E%3Cstrong%3EStarted%3A%20%3C%2Fstrong%3E2018%0D%3Cbr%3E%3Cstrong%3EFounder%3A%20%3C%2Fstrong%3ESiddiq%20Farid%20and%20Musfique%20Ahmed%0D%3Cbr%3E%3Cstrong%3EBased%3A%20%3C%2Fstrong%3EDubai%0D%3Cbr%3E%3Cstrong%3ESector%3A%20%3C%2Fstrong%3EFinTech%20%2F%20PropTech%0D%3Cbr%3E%3Cstrong%3EInitial%20investment%3A%20%3C%2Fstrong%3E%24650%2C000%0D%3Cbr%3E%3Cstrong%3ECurrent%20number%20of%20staff%3A%3C%2Fstrong%3E%2035%0D%3Cbr%3E%3Cstrong%3EInvestment%20stage%3A%20%3C%2Fstrong%3ESeries%20A%0D%3Cbr%3E%3Cstrong%3EInvestors%3A%20%3C%2Fstrong%3EVarious%20institutional%20investors%20and%20notable%20angel%20investors%20(500%20MENA%2C%20Shurooq%2C%20Mada%2C%20Seedstar%2C%20Tricap)%3C%2Fp%3E%0A
Key facilities
- Olympic-size swimming pool with a split bulkhead for multi-use configurations, including water polo and 50m/25m training lanes
- Premier League-standard football pitch
- 400m Olympic running track
- NBA-spec basketball court with auditorium
- 600-seat auditorium
- Spaces for historical and cultural exploration
- An elevated football field that doubles as a helipad
- Specialist robotics and science laboratories
- AR and VR-enabled learning centres
- Disruption Lab and Research Centre for developing entrepreneurial skills
The specs: 2019 Aston Martin DBS Superleggera
Price, base: Dh1.2 million
Engine: 5.2-litre twin-turbo V12
Transmission: Eight-speed automatic
Power: 725hp @ 6,500pm
Torque: 900Nm @ 1,800rpm
Fuel economy, combined: 12.3L / 100km (estimate)
Jetour T1 specs
Engine: 2-litre turbocharged
Power: 254hp
Torque: 390Nm
Price: From Dh126,000
Available: Now
Who is Allegra Stratton?
- Previously worked at The Guardian, BBC’s Newsnight programme and ITV News
- Took up a public relations role for Chancellor Rishi Sunak in April 2020
- In October 2020 she was hired to lead No 10’s planned daily televised press briefings
- The idea was later scrapped and she was appointed spokeswoman for Cop26
- Ms Stratton, 41, is married to James Forsyth, the political editor of The Spectator
- She has strong connections to the Conservative establishment
- Mr Sunak served as best man at her 2011 wedding to Mr Forsyth
The Sand Castle
Director: Matty Brown
Stars: Nadine Labaki, Ziad Bakri, Zain Al Rafeea, Riman Al Rafeea
Rating: 2.5/5
Killing of Qassem Suleimani
Killing of Qassem Suleimani
Breast cancer in men: the facts
1) Breast cancer is men is rare but can develop rapidly. It usually occurs in those over the ages of 60, but can occasionally affect younger men.
2) Symptoms can include a lump, discharge, swollen glands or a rash.
3) People with a history of cancer in the family can be more susceptible.
4) Treatments include surgery and chemotherapy but early diagnosis is the key.
5) Anyone concerned is urged to contact their doctor
HOW TO WATCH
Facebook: TheNationalNews
Twitter: @thenationalnews
Instagram: @thenationalnews.com
TikTok: @thenationalnews
Mohammed bin Zayed Majlis
UAE currency: the story behind the money in your pockets
The%20specs
%3Cp%3E%3Cstrong%3EEngine%3A%20%3C%2Fstrong%3E3.6-litre%2C%20V6%0D%3Cbr%3E%3Cstrong%3ETransmission%3A%20%3C%2Fstrong%3Eeight-speed%20auto%0D%3Cbr%3E%3Cstrong%3EPower%3A%20%3C%2Fstrong%3E285hp%0D%3Cbr%3E%3Cstrong%3ETorque%3A%20%3C%2Fstrong%3E353Nm%0D%3Cbr%3E%3Cstrong%3EPrice%3A%20%3C%2Fstrong%3EDh159%2C900%0D%3Cbr%3E%3Cstrong%3EOn%20sale%3A%20%3C%2Fstrong%3Enow%3C%2Fp%3E%0A
Kanguva
Director: Siva
Stars: Suriya, Bobby Deol, Disha Patani, Yogi Babu, Redin Kingsley
UAE currency: the story behind the money in your pockets
The National's picks
4.35pm: Tilal Al Khalediah
5.10pm: Continous
5.45pm: Raging Torrent
6.20pm: West Acre
7pm: Flood Zone
7.40pm: Straight No Chaser
8.15pm: Romantic Warrior
8.50pm: Calandogan
9.30pm: Forever Young
What is Reform?
Reform is a right-wing, populist party led by Nigel Farage, a former MEP who won a seat in the House of Commons last year at his eighth attempt and a prominent figure in the campaign for the UK to leave the European Union.
It was founded in 2018 and originally called the Brexit Party.
Many of its members previously belonged to UKIP or the mainstream Conservatives.
After Brexit took place, the party focused on the reformation of British democracy.
Former Tory deputy chairman Lee Anderson became its first MP after defecting in March 2024.
The party gained support from Elon Musk, and had hoped the tech billionaire would make a £100m donation. However, Mr Musk changed his mind and called for Mr Farage to step down as leader in a row involving the US tycoon's support for far-right figurehead Tommy Robinson who is in prison for contempt of court.
ANDROID%20VERSION%20NAMES%2C%20IN%20ORDER
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How%20I%20connect%20with%20my%20kids%20when%20working%20or%20travelling
%3Cp%3E%0D%3Cstrong%3ELittle%20notes%3A%20%3C%2Fstrong%3EMy%20girls%20often%20find%20a%20letter%20from%20me%2C%20with%20a%20joke%2C%20task%20or%20some%20instructions%20for%20the%20afternoon%2C%20and%20saying%20what%20I%E2%80%99m%20excited%20for%20when%20I%20get%20home.%0D%3Cbr%3E%3Cstrong%3EPhone%20call%20check-in%3A%20%3C%2Fstrong%3EMy%20kids%20know%20that%20at%203.30pm%20I%E2%80%99ll%20be%20free%20for%20a%20quick%20chat.%0D%3Cbr%3E%3Cstrong%3EHighs%20and%20lows%3A%20%3C%2Fstrong%3EInstead%20of%20a%20%E2%80%9Chow%20was%20your%20day%3F%E2%80%9D%2C%20at%20dinner%20or%20at%20bathtime%20we%20share%20three%20highlights%3B%20one%20thing%20that%20didn%E2%80%99t%20go%20so%20well%3B%20and%20something%20we%E2%80%99re%20looking%20forward%20to.%0D%3Cbr%3E%3Cstrong%3EI%20start%2C%20you%20next%3A%20%3C%2Fstrong%3EIn%20the%20morning%2C%20I%20often%20start%20a%20little%20Lego%20project%20or%20drawing%2C%20and%20ask%20them%20to%20work%20on%20it%20while%20I%E2%80%99m%20gone%2C%20then%20we%E2%80%99ll%20finish%20it%20together.%0D%3Cbr%3E%3Cstrong%3EBedtime%20connection%3A%20%3C%2Fstrong%3EWake%20up%20and%20sleep%20time%20are%20important%20moments.%20A%20snuggle%2C%20some%20proud%20words%2C%20listening%2C%20a%20story.%20I%20can%E2%80%99t%20be%20there%20every%20night%2C%20but%20I%20can%20start%20the%20day%20with%20them.%0D%3Cbr%3E%3Cstrong%3EUndivided%20attention%3A%20%3C%2Fstrong%3EPutting%20the%20phone%20away%20when%20I%20get%20home%20often%20means%20sitting%20in%20the%20car%20to%20send%20a%20last%20email%2C%20but%20leaving%20it%20out%20of%20sight%20between%20home%20time%20and%20bedtime%20means%20you%20can%20connect%20properly.%0D%3Cbr%3E%3Cstrong%3EDemystify%2C%20don%E2%80%99t%20demonise%20your%20job%3A%20%3C%2Fstrong%3EHelp%20them%20understand%20what%20you%20do%2C%20where%20and%20why.%20Show%20them%20your%20workplace%20if%20you%20can%2C%20then%20it%E2%80%99s%20not%20so%20abstract%20when%20you%E2%80%99re%20away%20-%20they%E2%80%99ll%20picture%20you%20there.%20Invite%20them%20into%20your%20%E2%80%9Cother%E2%80%9D%20world%20so%20they%20know%20more%20about%20the%20different%20roles%20you%20have.%3C%2Fp%3E%0A
Killing of Qassem Suleimani
The specs
Engine: 4.0-litre flat-six
Torque: 450Nm at 6,100rpm
Transmission: 7-speed PDK auto or 6-speed manual
Fuel economy, combined: 13.8L/100km
On sale: Available to order now
Match info
Bournemouth 0
Liverpool 4 (Salah 25', 48', 76', Cook 68' OG)
Man of the match: Andrew Robertson (Liverpool)
$1,000 award for 1,000 days on madrasa portal
Daily cash awards of $1,000 dollars will sweeten the Madrasa e-learning project by tempting more pupils to an education portal to deepen their understanding of math and sciences.
School children are required to watch an educational video each day and answer a question related to it. They then enter into a raffle draw for the $1,000 prize.
“We are targeting everyone who wants to learn. This will be $1,000 for 1,000 days so there will be a winner every day for 1,000 days,” said Sara Al Nuaimi, project manager of the Madrasa e-learning platform that was launched on Tuesday by the Vice President and Ruler of Dubai, to reach Arab pupils from kindergarten to grade 12 with educational videos.
“The objective of the Madrasa is to become the number one reference for all Arab students in the world. The 5,000 videos we have online is just the beginning, we have big ambitions. Today in the Arab world there are 50 million students. We want to reach everyone who is willing to learn.”
Company profile
Name: Oulo.com
Founder: Kamal Nazha
Based: Dubai
Founded: 2020
Number of employees: 5
Sector: Technology
Funding: $450,000
How to apply for a drone permit
- Individuals must register on UAE Drone app or website using their UAE Pass
- Add all their personal details, including name, nationality, passport number, Emiratis ID, email and phone number
- Upload the training certificate from a centre accredited by the GCAA
- Submit their request
What are the regulations?
- Fly it within visual line of sight
- Never over populated areas
- Ensure maximum flying height of 400 feet (122 metres) above ground level is not crossed
- Users must avoid flying over restricted areas listed on the UAE Drone app
- Only fly the drone during the day, and never at night
- Should have a live feed of the drone flight
- Drones must weigh 5 kg or less
How to wear a kandura
Dos
- Wear the right fabric for the right season and occasion
- Always ask for the dress code if you don’t know
- Wear a white kandura, white ghutra / shemagh (headwear) and black shoes for work
- Wear 100 per cent cotton under the kandura as most fabrics are polyester
Don’ts
- Wear hamdania for work, always wear a ghutra and agal
- Buy a kandura only based on how it feels; ask questions about the fabric and understand what you are buying
