Developing diabetes at a younger age increases the risk of dementia, new research suggests.
Research findings indicate that preventing progression from pre-diabetes to a diagnosis of Type 2 diabetes could mean a substantial reduction in future dementia cases, experts say.
Pre-diabetes is a condition where blood sugar is high but has not yet crossed the threshold for Type 2 diabetes.
It is linked with a high risk of progression to diabetes but is also independently associated with other changes in health.
Most people who develop diabetes first pass through pre-diabetes.
Among middle-aged adults with pre-diabetes, between 5 per cent and 10 per cent a year go on to develop Type 2 diabetes, with 70 per cent of those with pre-diabetes progressing to diabetes, the researchers say.
Research suggests that up to one third of the UK population may have pre-diabetes.
To look at the risk of dementia associated with pre-diabetes, the authors analysed data from people of the Atherosclerosis Risk in Communities study in the US.
According to the study there was a three times greater risk of dementia for those developing Type 2 diabetes before the age of 60.
This fell to a 73 per cent increased risk for those developing the condition aged 60-69 and a 23 per cent increased risk for those developing it at 70-79.
Foods that help to tackle diabetes - in pictures
The findings, published in Diabetologia, suggest that at ages 80 or older, developing diabetes was not associated with an increased risk of dementia.
“Our results suggest that aggressively managing pre-diabetes may be an important way to reduce dementia risk,” study co-author Dr Michael Fang, of Johns Hopkins Bloomberg School of Public Health, told The National.
“This is incredibly valuable given the large number of people with pre-diabetes around the world.
“Pre-diabetes currently impacts nearly 500 million adults, and this number is only set to increase."
The study by PhD student Jiaqi Hu and Prof Elizabeth Selvin of the Johns Hopkins Bloomberg school in the US, and colleagues, evaluated the association of pre-diabetes with dementia risk before and after accounting for the later development of Type 2 diabetes.
Among 11,656 people without diabetes to begin with, 2,330 (20 per cent) had pre-diabetes.
When accounting for diabetes that developed after the baseline period, the researchers found no statistically significant association between pre-diabetes and dementia.
But they found that earlier ages of progression to Type 2 diabetes had the strongest link with dementia.
“Diabetes prevention remains a major challenge across the world and more research is needed to understand how to effectively implement preventive policies and programmes,” Dr Fang said.
UAE currency: the story behind the money in your pockets
Six large-scale objects on show
- Concrete wall and windows from the now demolished Robin Hood Gardens housing estate in Poplar
- The 17th Century Agra Colonnade, from the bathhouse of the fort of Agra in India
- A stagecloth for The Ballet Russes that is 10m high – the largest Picasso in the world
- Frank Lloyd Wright’s 1930s Kaufmann Office
- A full-scale Frankfurt Kitchen designed by Margarete Schütte-Lihotzky, which transformed kitchen design in the 20th century
- Torrijos Palace dome
Like a Fading Shadow
Antonio Muñoz Molina
Translated from the Spanish by Camilo A. Ramirez
Tuskar Rock Press (pp. 310)
The specs: 2019 Subaru Forester
Price, base: Dh105,900 (Premium); Dh115,900 (Sport)
Engine: 2.5-litre four-cylinder
Transmission: Continuously variable transmission
Power: 182hp @ 5,800rpm
Torque: 239Nm @ 4,400rpm
Fuel economy, combined: 8.1L / 100km (estimated)
Ruwais timeline
1971 Abu Dhabi National Oil Company established
1980 Ruwais Housing Complex built, located 10 kilometres away from industrial plants
1982 120,000 bpd capacity Ruwais refinery complex officially inaugurated by the founder of the UAE Sheikh Zayed
1984 Second phase of Ruwais Housing Complex built. Today the 7,000-unit complex houses some 24,000 people.
1985 The refinery is expanded with the commissioning of a 27,000 b/d hydro cracker complex
2009 Plans announced to build $1.2 billion fertilizer plant in Ruwais, producing urea
2010 Adnoc awards $10bn contracts for expansion of Ruwais refinery, to double capacity from 415,000 bpd
2014 Ruwais 261-outlet shopping mall opens
2014 Production starts at newly expanded Ruwais refinery, providing jet fuel and diesel and allowing the UAE to be self-sufficient for petrol supplies
2014 Etihad Rail begins transportation of sulphur from Shah and Habshan to Ruwais for export
2017 Aldar Academies to operate Adnoc’s schools including in Ruwais from September. Eight schools operate in total within the housing complex.
2018 Adnoc announces plans to invest $3.1 billion on upgrading its Ruwais refinery
2018 NMC Healthcare selected to manage operations of Ruwais Hospital
2018 Adnoc announces new downstream strategy at event in Abu Dhabi on May 13
Source: The National
What went into the film
25 visual effects (VFX) studios
2,150 VFX shots in a film with 2,500 shots
1,000 VFX artists
3,000 technicians
10 Concept artists, 25 3D designers
New sound technology, named 4D SRL
Various Artists
Habibi Funk: An Eclectic Selection Of Music From The Arab World (Habibi Funk)
Ain Dubai in numbers
126: The length in metres of the legs supporting the structure
1 football pitch: The length of each permanent spoke is longer than a professional soccer pitch
16 A380 Airbuses: The equivalent weight of the wheel rim.
9,000 tonnes: The amount of steel used to construct the project.
5 tonnes: The weight of each permanent spoke that is holding the wheel rim in place
192: The amount of cable wires used to create the wheel. They measure a distance of 2,4000km in total, the equivalent of the distance between Dubai and Cairo.
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