The discovery of microplastics in human veins could assist in better results for cardiac bypass grafts. Reuters
The discovery of microplastics in human veins could assist in better results for cardiac bypass grafts. Reuters
The discovery of microplastics in human veins could assist in better results for cardiac bypass grafts. Reuters
The discovery of microplastics in human veins could assist in better results for cardiac bypass grafts. Reuters

Study discovers microplastics in human veins


Soraya Ebrahimi
  • English
  • Arabic

Microplastics that are used in food packaging and paint have been found in human veins, a study has discovered.

Microplastics can pass through blood vessels to vascular tissue, results suggest, but scientists said it was not yet clear what the implications were for human health.

Human saphenous vein tissue taken from patients undergoing heart bypass surgery was assessed in a small pilot study by a team from the University of Hull and Hull York Medical School, and from the Hull University Teaching Hospitals NHS Trust.

They found 15 microplastic particles for every gram of vein tissue and five different polymer types.

The most prominent included alkyd resin, used in synthetic paint, varnishes and enamels; polyvinyl acetate, an adhesive found in food packaging and nylon; and EVOH and EVA, used in flexible packaging materials.

“We were surprised to find them. We already know microplastics are in blood, from a study by Dutch colleagues last year," said Prof Jeanette Rotchell, an environmental toxicologist at the University of Hull.

“But it was not clear whether they could cross blood vessels into vascular tissue and this work would suggest they can do just that.

“Whilst we don’t yet know the implications of this on human health, what we can say is that from studies using cells grown in dishes, they cause inflammation and stress responses.”

The study, published in the journal Plos One, showed the levels of microplastics observed were similar to, or higher than, those reported for colon and lung tissues.

Saphenous veins are blood vessels in the legs, which help to send blood from the legs and feet back up to the heart.

The veins consist of three layers of tissue and are widely used in coronary artery bypass graft (CABG) procedures.

About 40 to 50 per cent of CABG procedures ultimately fail after 10 years because of a variety of factors, which are not always clear.

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Until now, no studies have examined whether microplastics can infiltrate or cross any biological barrier, including blood vessels, or any possible link between environmental microplastic exposure and CABG results.

“The characterisation of types and levels of microplastics can now inform experiments to determine vascular health impacts, including any potential link between environmental microplastic exposure and CABG outcomes," said Prof Rotchell.

Prof Mahmoud Loubani, a co-author and honorary professor of cardiothoracic surgery, said: "Failure of saphenous vein grafts has been a long-standing issue following coronary artery bypass surgery.

"It is an effective treatment but the longevity is limited by deterioration in the patency of the veins.

“The presence of these microplastics in the veins may well play a role in damaging the inside of the vein, leading to it becoming blocked with the passage of time.

"We do need to identify if there is any correlation and figure out ways of maybe removing the microplastics.”

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Key findings of Jenkins report
  • Founder of the Muslim Brotherhood, Hassan al Banna, "accepted the political utility of violence"
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March 8-9 UAE Rotax Max Challenge

What the law says

Micro-retirement is not a recognised concept or employment status under Federal Decree Law No. 33 of 2021 on the Regulation of Labour Relations (as amended) (UAE Labour Law). As such, it reflects a voluntary work-life balance practice, rather than a recognised legal employment category, according to Dilini Loku, senior associate for law firm Gateley Middle East.

“Some companies may offer formal sabbatical policies or career break programmes; however, beyond such arrangements, there is no automatic right or statutory entitlement to extended breaks,” she explains.

“Any leave taken beyond statutory entitlements, such as annual leave, is typically regarded as unpaid leave in accordance with Article 33 of the UAE Labour Law. While employees may legally take unpaid leave, such requests are subject to the employer’s discretion and require approval.”

If an employee resigns to pursue micro-retirement, the employment contract is terminated, and the employer is under no legal obligation to rehire the employee in the future unless specific contractual agreements are in place (such as return-to-work arrangements), which are generally uncommon, Ms Loku adds.

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Updated: February 01, 2023, 10:24 PM`