A company that uses artificial intelligence to speed up drug trials will open a research centre in Abu Dhabi.
Quris-AI signed an agreement with the Mohamed bin Zayed University of Artificial Intelligence this week to develop a bio-AI centre in the capital.
The Tel Aviv and Boston-based company recently attracted tens of millions of dollars in funding for its “patient-on-a-chip” technology, with Softbank's Vision Fund among the investors.
Quris research operations are led by Nobel laureate Prof Aaron Ciechanover and Moderna co-founder Prof Robert Langer.
One compelling aspect of my discussions has been about solving UAE-specific health problems faster and more cost-effectively
Prof Eric Xing,
Mohamed bin Zayed University of Artificial Intelligence
Prof Eric Xing, the university's president, said together the two parties would look at how drugs could be tailored for patient use in the UAE.
“One compelling aspect of my discussions with Prof Ciechanover and the Quris team has been about solving UAE-specific health problems faster and more cost-effectively,” Dr Xing said.
The “patient-on-a-chip” technique involves rapid tests using AI technology that simulates genetically diverse patients.
This negates the need for animal testing and avoids the risk and cost associated with failed clinical trials.
The average cost of developing a new drug from scratch takes a decade and costs $2.8 billion. Even then, about 90 per cent of new drugs fail the second stage of clinical trials.
“The organelle systems being developed at Quris are a revolutionary platform for high-throughput drug testing, which can be best served by a similarly high-throughput drug design pipeline using AI,” Prof Xing said.
“Our unique capacities in computational biology and machine learning at MBZUAI will enhance Quris’ efforts to accelerate the development of new personalised and potentially life-saving medicines.”
Dr Isaac Bentwich, founder and chief executive of Quris, said the centre was the latest step in UAE's ambitions to “to become a centre of excellence in AI as a strong pillar of the economy, and we are honoured to contribute to realising this vision”.
Dr Bentwich has previously likened drug testing to building 10 tower blocks, with the knowledge that “nine will crumble”.
“But you have no idea which ones will fall, so all you can do is build them and charge a higher rent on the one that keeps standing,” he said at the time.
“That's the problem we are trying to solve.”
As of December 2022, Quris had attracted $37 million in seed funding, including $9 million from Japan's SoftBank.
Former Pfizer chief executive Henry McKinnell is chairman of the Quris Advisory Board, alongside Dr Kobi Richter, founder of world-leading companies Medinol and Orbotech.
Killing of Qassem Suleimani
SPEC%20SHEET%3A%20SAMSUNG%20GALAXY%20S24%20ULTRA
%3Cp%3E%3Cstrong%3EDisplay%3A%3C%2Fstrong%3E%206.8%22%20quad-HD%2B%20dynamic%20Amoled%202X%2C%203120%20x%201440%2C%20505ppi%2C%20HDR10%2B%2C%20120Hz%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EProcessor%3A%3C%2Fstrong%3E%204nm%20Qualcomm%20Snapdragon%208%20Gen%203%2C%2064-bit%20octa-core%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EMemory%3A%3C%2Fstrong%3E%2012GB%20RAM%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EStorage%3A%3C%2Fstrong%3E%20256%2F512GB%20%2F%201TB%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EPlatform%3A%3C%2Fstrong%3E%20Android%2014%2C%20One%20UI%206.1%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EMain%20camera%3A%3C%2Fstrong%3E%20quad%20200MP%20wide%20f%2F1.7%20%2B%2050MP%20periscope%20telephoto%20f%2F3.4%20with%205x%20optical%2F10x%20optical%20quality%20zoom%20%2B%2010MP%20telephoto%202.4%20with%203x%20optical%20zoom%20%2B%2012MP%20ultra-wide%20f%2F2.2%3B%20100x%20Space%20Zoom%3B%20auto%20HDR%2C%20expert%20RAW%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EVideo%3A%3C%2Fstrong%3E%208K%4024%2F30fps%2C%204K%4030%2F60%2F120fps%2C%20full-HD%4030%2F60%2F240fps%2C%20full-HD%20super%20slo-mo%40960fps%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EFront%20camera%3A%3C%2Fstrong%3E%2012MP%20f%2F2.2%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EBattery%3A%3C%2Fstrong%3E%205000mAh%2C%20fast%20wireless%20charging%202.0%2C%20Wireless%20PowerShare%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EConnectivity%3A%3C%2Fstrong%3E%205G%2C%20Wi-Fi%2C%20Bluetooth%205.3%2C%20NFC%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EI%2FO%3A%3C%2Fstrong%3E%20USB-C%3B%20built-in%20Galaxy%20S%20Pen%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EDurability%3A%3C%2Fstrong%3E%20IP68%2C%20up%20to%201.5m%20of%20freshwater%20up%20to%2030%20minutes%3B%20dust-resistant%26nbsp%3B%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3ESIM%3A%3C%2Fstrong%3E%20Nano%20%2B%20nano%20%2F%20nano%20%2B%20eSIM%20%2F%20dual%20eSIM%20(varies%20in%20different%20markets)%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EColours%3A%3C%2Fstrong%3E%20Titanium%20black%2C%20titanium%20grey%2C%20titanium%20violet%2C%20titanium%20yellow%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EIn%20the%20box%3A%20%3C%2Fstrong%3EGalaxy%20S24%20Ultra%2C%20USB-C-to-C%20cable%26nbsp%3B%3C%2Fp%3E%0A%3Cp%3E%3Cstrong%3EPrice%3A%3C%2Fstrong%3E%20Dh5%2C099%20for%20256GB%2C%20Dh5%2C599%20for%20512GB%2C%20Dh6%2C599%20for%201TB%3C%2Fp%3E%0A
RESULTS
Bantamweight:
Zia Mashwani (PAK) bt Chris Corton (PHI)
Super lightweight:
Flavio Serafin (BRA) bt Mohammad Al Khatib (JOR)
Super lightweight:
Dwight Brooks (USA) bt Alex Nacfur (BRA)
Bantamweight:
Tariq Ismail (CAN) bt Jalal Al Daaja (JOR)
Featherweight:
Abdullatip Magomedov (RUS) bt Sulaiman Al Modhyan (KUW)
Middleweight:
Mohammad Fakhreddine (LEB) bt Christofer Silva (BRA)
Middleweight:
Rustam Chsiev (RUS) bt Tarek Suleiman (SYR)
Welterweight:
Khamzat Chimaev (SWE) bt Mzwandile Hlongwa (RSA)
Lightweight:
Alex Martinez (CAN) bt Anas Siraj Mounir (MAR)
Welterweight:
Jarrah Al Selawi (JOR) bt Abdoul Abdouraguimov (FRA)
UAE currency: the story behind the money in your pockets
Killing of Qassem Suleimani
What the law says
Micro-retirement is not a recognised concept or employment status under Federal Decree Law No. 33 of 2021 on the Regulation of Labour Relations (as amended) (UAE Labour Law). As such, it reflects a voluntary work-life balance practice, rather than a recognised legal employment category, according to Dilini Loku, senior associate for law firm Gateley Middle East.
“Some companies may offer formal sabbatical policies or career break programmes; however, beyond such arrangements, there is no automatic right or statutory entitlement to extended breaks,” she explains.
“Any leave taken beyond statutory entitlements, such as annual leave, is typically regarded as unpaid leave in accordance with Article 33 of the UAE Labour Law. While employees may legally take unpaid leave, such requests are subject to the employer’s discretion and require approval.”
If an employee resigns to pursue micro-retirement, the employment contract is terminated, and the employer is under no legal obligation to rehire the employee in the future unless specific contractual agreements are in place (such as return-to-work arrangements), which are generally uncommon, Ms Loku adds.
What can victims do?
Always use only regulated platforms
Stop all transactions and communication on suspicion
Save all evidence (screenshots, chat logs, transaction IDs)
Report to local authorities
Warn others to prevent further harm
Courtesy: Crystal Intelligence
'Worse than a prison sentence'
Marie Byrne, a counsellor who volunteers at the UAE government's mental health crisis helpline, said the ordeal the crew had been through would take time to overcome.
“It was worse than a prison sentence, where at least someone can deal with a set amount of time incarcerated," she said.
“They were living in perpetual mystery as to how their futures would pan out, and what that would be.
“Because of coronavirus, the world is very different now to the one they left, that will also have an impact.
“It will not fully register until they are on dry land. Some have not seen their young children grow up while others will have to rebuild relationships.
“It will be a challenge mentally, and to find other work to support their families as they have been out of circulation for so long. Hopefully they will get the care they need when they get home.”
MATCH INFO
Manchester City 4 (Gundogan 8' (P), Bernardo Silva 19', Jesus 72', 75')
Fulham 0
Red cards: Tim Ream (Fulham)
Man of the Match: Gabriel Jesus (Manchester City)
THE SPECS
Engine: 4.0L twin-turbo V8
Gearbox: eight-speed automatic
Power: 571hp at 6,000rpm
Torque: 800Nm from 2,000-4,500rpm
Fuel economy, combined: 11.4L/100km
Price, base: from Dh571,000
On sale: this week
What is graphene?
Graphene is a single layer of carbon atoms arranged like honeycomb.
It was discovered in 2004, when Russian-born Manchester scientists Andrei Geim and Kostya Novoselov were "playing about" with sticky tape and graphite - the material used as "lead" in pencils.
Placing the tape on the graphite and peeling it, they managed to rip off thin flakes of carbon. In the beginning they got flakes consisting of many layers of graphene. But as they repeated the process many times, the flakes got thinner.
By separating the graphite fragments repeatedly, they managed to create flakes that were just one atom thick. Their experiment had led to graphene being isolated for the very first time.
At the time, many believed it was impossible for such thin crystalline materials to be stable. But examined under a microscope, the material remained stable, and when tested was found to have incredible properties.
It is many times times stronger than steel, yet incredibly lightweight and flexible. It is electrically and thermally conductive but also transparent. The world's first 2D material, it is one million times thinner than the diameter of a single human hair.
But the 'sticky tape' method would not work on an industrial scale. Since then, scientists have been working on manufacturing graphene, to make use of its incredible properties.
In 2010, Geim and Novoselov were awarded the Nobel Prize for Physics. Their discovery meant physicists could study a new class of two-dimensional materials with unique properties.
Specs
Engine: Dual-motor all-wheel-drive electric
Range: Up to 610km
Power: 905hp
Torque: 985Nm
Price: From Dh439,000
Available: Now
500 People from Gaza enter France
115 Special programme for artists
25 Evacuation of injured and sick
Heavily-sugared soft drinks slip through the tax net
Some popular drinks with high levels of sugar and caffeine have slipped through the fizz drink tax loophole, as they are not carbonated or classed as an energy drink.
Arizona Iced Tea with lemon is one of those beverages, with one 240 millilitre serving offering up 23 grams of sugar - about six teaspoons.
A 680ml can of Arizona Iced Tea costs just Dh6.
Most sports drinks sold in supermarkets were found to contain, on average, five teaspoons of sugar in a 500ml bottle.
A State of Passion
Directors: Carol Mansour and Muna Khalidi
Stars: Dr Ghassan Abu-Sittah
Rating: 4/5
