The coronavirus pandemic probably arose from a Chinese laboratory leak, the US Department of Energy announced on Sunday, although sources who have seen its classified report said the agency made its judgment with "low confidence".
The White House maintained that US intelligence remained divided on the issue.
The Wall Street Journal reported that the conclusion marks a shift by the energy department, which had previously said it was undecided how the virus emerged.
The conclusion, reportedly the result of new intelligence, is nevertheless significant because the department oversees a network of national laboratories, including some that conduct advanced biological research.
The FBI believes that the pandemic, which has left nearly seven million people dead, was the result of a mishap in a Chinese laboratory.
But four US intelligence agencies believe Covid occurred through natural transmission, while two others remain undecided, the Journal reported.
Shanghai Covid-19 lockdown - in pictures
White House National Security Adviser Jake Sullivan stressed that a "variety of views" on the matter remain.
"Right now, there is not a definitive answer that has emerged from the intelligence community on this question," Mr Sullivan told CNN.
In mid-February, the World Health Organisation pledged to do everything possible "until we get the answer" on Covid's origins, denying a report saying it had abandoned its investigation.
The scientific community considers it crucial to determine the origins of the pandemic to better fight or even prevent the next one.
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Book: “Das Kapital, by Karl Marx. I am not a communist, but there are a lot of lessons for the capitalist system, if you let it get out of control, and humanity.”
Musician: “I like very much Fairuz, the Lebanese singer, and the other is Umm Kulthum. Fairuz is for listening to in the morning, Umm Kulthum for the night.”
Countries recognising Palestine
France, UK, Canada, Australia, Portugal, Belgium, Malta, Luxembourg, San Marino and Andorra
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• Scientists estimate there could be as many as 3 million fungal species globally
• Only about 160,000 have been officially described leaving around 90% undiscovered
• Fungi account for roughly 90% of Earth's unknown biodiversity
• Forest fungi help tackle climate change, absorbing up to 36% of global fossil fuel emissions annually and storing around 5 billion tonnes of carbon in the planet's topsoil
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Muslim Council of Elders condemns terrorism on religious sites
The Muslim Council of Elders has strongly condemned the criminal attacks on religious sites in Britain.
It firmly rejected “acts of terrorism, which constitute a flagrant violation of the sanctity of houses of worship”.
“Attacking places of worship is a form of terrorism and extremism that threatens peace and stability within societies,” it said.
The council also warned against the rise of hate speech, racism, extremism and Islamophobia. It urged the international community to join efforts to promote tolerance and peaceful coexistence.